Advances of Betalains Biosynthesis and Metabolic Regulation

doi:10.13523/j.cb.20180811

China Biotechnology

2018, Vol. 38

Issue (8): 84-91 DOI: 10.13523/j.cb.20180811

Advances of Betalains Biosynthesis and Metabolic Regulation

Si-li YU¹,Xue LIU¹,Zhao-yu ZHANG¹,Hong-jian YU²,Guang-rong ZHAO^1,**(

)

^1. Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin 300350, China
^2. Ubasio Biotech Co., Ltd., Tianjin 300450, China

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Abstract

Betalains is a kind of botanical water-soluble natural nitrogen-containing pigments, which used as food additives and cosmetics. Betalains and anthocyanin pigments do not coexist in a same plant, and their metabolic pathway is an important phytochemical classification index. Betalains have potential pharmacological effects of anti-tumor, anti-oxidation, anti-malaria and liver protective, which have promoted the further study of them. The key enzymes of betalains synthesis pathway and research progress of synthetic biology strategy for betalains production at home and abroad are reviewed. It provides a reference for establishing synthetic biological method of betalains production.

Key words： Betalains biosynthesis Synthetic biology Metabolic engineering Betanin Betaxanthin

Received: 08 April 2018 Published: 11 September 2018

ZTFLH:

Q946

Corresponding Authors: Guang-rong ZHAO E-mail: grzhao@tju.edu.cn

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	Si-li YU
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	Zhao-yu ZHANG
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	Guang-rong ZHAO

Cite this article:

Si-li YU,Xue LIU,Zhao-yu ZHANG,Hong-jian YU,Guang-rong ZHAO. Advances of Betalains Biosynthesis and Metabolic Regulation. China Biotechnology, 2018, 38(8): 84-91.

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https://manu60.magtech.com.cn/biotech/10.13523/j.cb.20180811 OR https://manu60.magtech.com.cn/biotech/Y2018/V38/I8/84

Fig.1 Biosynthesis pathway of betalains 5-GT: Betanidin-5-O-glycosyltransferase; 6-GT: Betanidin-6-O-glycosyltransferase

Table 1 Common betalains and their source

Table 2 Synthesis of betalains from non-caryophyllales plants


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