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| Mesenchymal Stem Cells Secretome: A Novel Alternate Therapy for Wound Healing |
| LIN Ji-zhi1, WANG Qiang2, DIAO Yong3 |
1 Department of Scientific Research, Huaqiao University, Quanzhou 362021, China;
2 QuanZhou Women's and Children's Hospital, Quanzhou 362000, China;
3 School of Biomedical Science, Institutes of Molecular Medicine, Huaqiao University, Quanzhou 362021, China |
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Abstract There is a growing body of evidence supporting the paracrine/autocrine activity of mesenchymal stem cells (MSCs) exerts therapeutic benefits, which could be related to angiogenesis, immune modulation and regulation of apoptosis. Bioactive molecules secreted by MSCs, which is named as secretome, includes cytokines, chemokines and growth factors, and has gained increasing attention in recent years because of its multiple implications for the repair, restoration or regeneration of injured tissues. Based on its molecule profiling and regulation role of many physiological processes, MSCs secretome has shown great potential as a novel and promising alternative to skin wound healing treatment.
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Received: 02 November 2016
Published: 25 April 2017
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