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中国生物工程杂志

China Biotechnology
China Biotechnology  2011, Vol. 31 Issue (06): 129-134    DOI:
    
The Research of Mesenchymal Stem Cells Differentiate Chondrocytes
LIU Jing1, YU Li1, XU Chao2
1. Biochemistry Department of Medical College, Jinan University, Guangzhou 510632, China;
2. Tin Ka Ping Center for Medical Experiment of Medical College, Jinan University, Guangzhou 510632, China
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Abstract  

Articular cartilage has limited ability to repair and regeneration by itself. At present, the clinical treatment and drugs for articular cartilage injury are difficult to achieve satisfactory results. Mesenchymal stem cells present themselves as a promising cell source for cartilage tissue engineering, because they have great potential for multilineage differentiation, expandable in vitro without losing their differentiation type, low immunogenicity and easily obtainable in high numbers. The Mesenchymal stem cells differentiate chondrocytes was focused on and many effect factors of Mesenchymal stem cells differentiate chondrocytes, such as growth factor, oxygen concentration, scaffold and so on were systematically introduced. In addition, some opinions on MSCs as seed cells present disease and development for cartilage tissue engineering were given.



Key wordsMesenchymal stem cells      Chondrocytes      Differentiation      Effect factor     
Received: 29 November 2010      Published: 28 June 2011
ZTFLH:  Q819  
Cite this article:

LIU Jing, YU Li, XU Chao. The Research of Mesenchymal Stem Cells Differentiate Chondrocytes. China Biotechnology, 2011, 31(06): 129-134.

URL:

https://manu60.magtech.com.cn/biotech/     OR     https://manu60.magtech.com.cn/biotech/Y2011/V31/I06/129

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