Research Progress of in the Inducers Stimulating in Differentiation of iPS Cells into Male Germ Cells

doi:10.13523/j.cb.20190412

China Biotechnology

2019, Vol. 39

Issue (4): 94-100 DOI: 10.13523/j.cb.20190412

Research Progress of in the Inducers Stimulating in Differentiation of iPS Cells into Male Germ Cells

Xin LI¹,Zhong-li ZHAO¹,Xiao-tong LUO²,Yang CAO¹,Li-chun ZHANG¹,Yong-sheng YU^1**(

),Hai-guo JIN^1**(

)

1 Branch of Animal Husbandry, Jilin Academy of Agricultural Sciences, Gongzhuling 136100,China
2 Agricultural College, Yan Bian University, Yanji 133002, China

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Abstract

Induced pluripotent stem cells(iPSCs) refer to stem cells that are artificially produced by cellular reprogramming, which have similar functions to embryonic stem cells. They can differentiate into all cell types, and avoid the ethical controversy of ESCs and immune rejection after transplantation. They have a broad application prospect.The advances in the in vitro differentiation of male germ cells using iPSCs by different inducers was reviewed, the effect was also investigated. Exploring development mechanisms of germ cells is promising to promote future reproductive and developmental engineering technologies.

Key words： iPSCs Male germ cells Differentiation Inducers

Received: 27 September 2018 Published: 08 May 2019

ZTFLH:

Q813.5

Corresponding Authors: Yong-sheng YU,Hai-guo JIN E-mail: yuyongsheng2002@163.com;khk1962@126.com

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	Xin LI
	Zhong-li ZHAO
	Xiao-tong LUO
	Yang CAO
	Li-chun ZHANG
	Yong-sheng YU
	Hai-guo JIN

Cite this article:

Xin LI,Zhong-li ZHAO,Xiao-tong LUO,Yang CAO,Li-chun ZHANG,Yong-sheng YU,Hai-guo JIN. Research Progress of in the Inducers Stimulating in Differentiation of iPS Cells into Male Germ Cells. China Biotechnology, 2019, 39(4): 94-100.

URL:

https://manu60.magtech.com.cn/biotech/10.13523/j.cb.20190412 OR https://manu60.magtech.com.cn/biotech/Y2019/V39/I4/94

Fig.1 Differentiation of iPS into male germ cells


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