Progress and Prospect of Chitin Deacetylase

doi:10.13523/j.cb.20150114

China Biotechnology

2015, Vol. 35

Issue (1): 96-103 DOI: 10.13523/j.cb.20150114

Progress and Prospect of Chitin Deacetylase

WANG Hao, WU Li, ZHU Xiao-hua, LIU Wang-wang, YANG Gong-ming

Collage of Food Science, South China Agricultural University, Guangzhou 510642, China

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Abstract

Chitin deacetylase(CDA,E.C.3.5.1.41)is an enzyme that catalyzes the hydrolysis of acetamine groups of N-glucosamine in chitin, promoting the conversion to chitosan, a glucosamine polymer. Because of its unique properties,chitosan is widely used in medicine, food, chemical, cosmetics and so on. The present researches on CDA are reviewed. It includes the source, the purification and characterization, the structure and catalytic mechanism,the expression of gene cloning and applications prospect of the CDA, with analyzing the main research direction in the future are the expression of gene cloning, substrate modification and structure and catalytic mechanism of CDA.

Key words： Chitin deacetylase Chitin Chitosan Deacetylation

Received: 02 September 2014 Published: 25 January 2015

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WANG Hao, WU Li, ZHU Xiao-hua, LIU Wang-wang, YANG Gong-ming. Progress and Prospect of Chitin Deacetylase. China Biotechnology, 2015, 35(1): 96-103.

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https://manu60.magtech.com.cn/biotech/10.13523/j.cb.20150114 OR https://manu60.magtech.com.cn/biotech/Y2015/V35/I1/96

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