Research Progress on the Biological Fermentation of Xylitol

doi:OI:10.13523/j.cb.1907021

China Biotechnology

2020, Vol. 40

Issue (3): 144-153 DOI: OI:10.13523/j.cb.1907021

Orginal Article

Research Progress on the Biological Fermentation of Xylitol

WANG Meng,ZHANG Quan,GAO Hui-peng,GUAN Hao,CAO Chang-hai(

)

Key Laboratory of Biofuels and Biochemical Engineering, Dalian Research Institute of Petroleum and Petrochemicals, SINOPEC, Dalian 116045, China

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Abstract

Xylitol is widely used in various fields because of its special physical and chemical properties, the global demand is increasing day by day. At present, the industrial production method of xylitol is produced by pure D-xylose under high temperature and pressure by chemical catalysis. There are many problems such as high requirements for raw materials, high energy consumption, rigorous conditions and heavy pollution. Biological fermentation technology can produce xylitol from low-cost crop waste fermented by strains. It has attracted much attention because of its wide source of raw materials, low energy consumption, mild condition and friendly environment, is a potentially attractive alternative to chemical processes. However, due to the low content of xylitol in fermentation products, the route of microbial fermentation to prepare xylitol has not been practiced in industry. The influencing factors in the process of bio-synthesis of xylitol and the possible technology of strain modification were reviewed. The challenges and prospects of bioproduction of xylitol were presented, and the research direction of biosynthesis of xylitol was prospected.

Key words： Microorganism Fermentation Xylitol

Received: 10 July 2019 Published: 18 April 2020

ZTFLH:

Q815

Corresponding Authors: Chang-hai CAO E-mail: fshy@sinopec.com

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	Meng WANG
	Quan ZHANG
	Hui-peng GAO
	Hao GUAN
	Chang-hai CAO

Cite this article:

WANG Meng,ZHANG Quan,GAO Hui-peng,GUAN Hao,CAO Chang-hai. Research Progress on the Biological Fermentation of Xylitol. China Biotechnology, 2020, 40(3): 144-153.

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https://manu60.magtech.com.cn/biotech/OI:10.13523/j.cb.1907021 OR https://manu60.magtech.com.cn/biotech/Y2020/V40/I3/144

Table 1 Comparison of xylitol production from different substrates by yeasts

Fig.1 Xylose and glucose metabolic pathway in yeast


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