动物细胞大规模培养技术

中国生物工程杂志

2012, Vol. 32

Issue (07): 127-132

综述

动物细胞大规模培养技术

梅建国^1,2, 庄金秋^1,2, 王金良², 王玉茂², 丁壮¹, 沈志强²

1. 吉林大学畜牧兽医学院长春 130062;
2. 山东省滨州畜牧兽医研究院滨州 256600

Advance of Large-scale Animal Cell Culture Technology

MEI Jian-guo^1,2, ZHUANG Jin-qiu^1,2, WANG Jin-liang², WANG Yu-mao², DING Zhuang¹, SHEN Zhi-qiang²

1. College of Animal Science and Veterinary Medicine, Jilin University, Jilin 130062, China;
2. Shandong Binzhou Animal Science & Veterinary Medicine Insitute, Binzhou 256600, China

全文: PDF(406 KB) HTML

摘要： 近年来,动物细胞大规模培养技术在生物技术领域成为最受关注的热点之一,并开始广泛应用于生物医药的研发和生产过程中。以生物反应器技术为基础的动物细胞大规模培养技术平台,正逐步被建立起来并日益走向成熟,成为推动生物医药产业快速发展的有力工具。结合该技术目前的应用水平和最新进展,分析了不同细胞培养工艺之间的内在差异,以探索这一技术的未来发展方向。

关键词： 动物细胞; 大规模培养; 生物反应器; 生物医药

Abstract: In recent years, large-scale animal cell culture technology in the field of biotechnology as one of the most talked about hot spots, have been widely used in the process of the biomedical research and production. Large-scale animal cell culture technology platform based on bio-reactor technology is being built up gradually and becoming increasingly mature, which will become the powerful tools promoting bio-pharmaceutical industry rapid development. Focusing on the application level of this technology and its recent progress,the differences among the different cell culture technology are analyzed for finding its future direction.

Key words: Animal cells Large-scale cultivation Bioreactor Biomedical

收稿日期: 2011-12-12 出版日期: 2012-07-25

ZTFLH:

Q813

通讯作者: 丁壮, 沈志强 E-mail: ding_zhuang@yahoo.com.cn; bzshenzq@vip.sina.com

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引用本文:

梅建国, 庄金秋, 王金良, 王玉茂, 丁壮, 沈志强. 动物细胞大规模培养技术[J]. 中国生物工程杂志, 2012, 32(07): 127-132.

MEI Jian-guo, ZHUANG Jin-qiu, WANG Jin-liang, WANG Yu-mao, DING Zhuang, SHEN Zhi-qiang. Advance of Large-scale Animal Cell Culture Technology. China Biotechnology, 2012, 32(07): 127-132.

链接本文:

https://manu60.magtech.com.cn/biotech/CN/ 或 https://manu60.magtech.com.cn/biotech/CN/Y2012/V32/I07/127

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