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中国生物工程杂志

CHINA BIOTECHNOLOGY
中国生物工程杂志  2009, Vol. 29 Issue (11): 117-122    
综述     
红曲桔霉素的控制对策
刘畅,葛锋**,刘迪秋,王剑平,陈朝银
昆明理工大学生命科学与技术学院 昆明 650224
The Strategy of Citrinin Production Control in Monascus
LIU Chang,GE Feng,LIU Di-qiu,WANG Jian-ping,CHEN Chao-yin
1.Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650224, China
 全文: PDF(586 KB)   HTML
摘要:

红曲的药用价值和保健功能日益引人关注,然而红曲中桔霉素的存在严重制约着红曲产品的开发,如何降低红曲桔霉素的含量是一个迫切需要解决的问题。本文概述了红曲桔霉素的毒性、生物合成途径及相关标准。并结合国内外研究进展,从发酵工艺,诱变育种,基因工程三个层面阐述了控制红曲桔霉素产生的对策,并对桔霉素今后的研究方向进行了展望。

关键词: 桔霉素红曲发酵工艺诱变育种基因工程    
Abstract:

Pepole pay more attention to the medicinal value and health function of Monascus day by day,however,the existence of citrinin restricted the further development of Monascus products heavily. How to ruduce the content of citrinin is a problem need to be solved urgently. This paper briefly introduced the toxicity, the biosynthetic pathway, and the relative standards of citrinin in monascus. According to the research progress on citrinin, the strategies of citrinin control were described from the three aspects of fermentation technology, mutation breeding, and genetic engineering. The expectation about the direction of citrinin in the future was also discussed.

Key words: Citrinin    Monascus    Fermentation process    mutation breeding    Genetic engineering
收稿日期: 2009-06-05 出版日期: 2009-12-07
ZTFLH:  Q815  
基金资助:

科技部中小企业创新基金资助项目(07C26215301962)

通讯作者: 葛锋     E-mail: gefeng79@yahoo.com.cn
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引用本文:

刘畅 葛锋 刘迪秋 王剑平 陈朝银. 红曲桔霉素的控制对策[J]. 中国生物工程杂志, 2009, 29(11): 117-122.

LIU Chang. The Strategy of Citrinin Production Control in Monascus. China Biotechnology, 2009, 29(11): 117-122.

链接本文:

https://manu60.magtech.com.cn/biotech/CN/        https://manu60.magtech.com.cn/biotech/CN/Y2009/V29/I11/117

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