生物反应器是生物工程的核心设备,其结构的合理性直接决定反应器生物加工的效率。生物反应器的研究一直是生物工程的核心问题之一。随着青霉素的工业化生产,机械搅拌式生物反应器应运而生,此后,随着动植物细胞培养,高等真菌培养,藻类培养等生物过程的发展,人们相应开发了大量的生物反应器,其中以机械搅拌式生物反应器和气升式样生物反应器尤为突出,本文总结了近年来文献报道的新型生物反应器,主要阐述了机械搅拌式和气升式两类生物反应器结构的研究进展,对目前国内外报道的11种新型反应器典型结构进行了总结与分析。
Bioreactor is a key equipment in bioengineering. The bioprocessing efficiency using bioreactors is significantly affected by the reactor configuration. It is apparent that research on the bioreactor structure is one of key issues in bioengineering. Along with industrialization of penicillin mechanically stirred bioreactor was developed, after that large quantity of bioreactors was invented for the sake of the development of mammal and plant cell cultivation ,epiphyte cultivation and algae cultivation. Among these bioreactors mechanical stirred bioreactors and airlift bioreactors are very popular. This article reviews recent trends of studies on mechanically stirred bioreactors and air-lift ones. Our focus is on the summarization and analysis of 11 kinds of novel bioreactors developed around the world.
唐江伟,吴振强. 新型生物反应器结构研究进展[J]. 中国生物工程杂志, 2007, 27(5): 146-152.
. Advances in Bioreactor Structure Innovation and Related Studies. China Biotechnology, 2007, 27(5): 146-152.
https://manu60.magtech.com.cn/biotech/CN/ 或 https://manu60.magtech.com.cn/biotech/CN/Y2007/V27/I5/146
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