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| A Novel Technology for Removing Potential Risks from Genetically Modified Plants |
| National Engineering Laboratory for Tree Breeding, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants,Ministry of Education, Beijing Forestry University, Beijing 100083, China |
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Abstract Scientists have been searching an effective tool for solving the safety issue of GM (genetically modified) crops for many years. The group led by Chinese American scientist Yi Li, a professor at University of Connecticut, made a great breakthrough in this field after 6 years’ intensive research: his group published the “Gene-deletor” technology in 2007. The technology was developed from two recombination systems Cre/LoxP and FLP/FRT, and FLP/Cre was driven by Organ/Tissue-specific promoter, all transgenic foreign genes will be thoroughly removed from pollen, fruit and seed after they have accomplished function. It could effectively prevent GM gene flow into non-biotech crops or weeds, and may help alleviate public concerns on ecological risks and food safety caused by GM plants. Here, we introduce the concept, principle of “gene-deletor” technology and discuss its applications in genetic engineering research.
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Received: 07 December 2009
Published: 26 February 2010
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