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中国生物工程杂志

China Biotechnology
China Biotechnology  2016, Vol. 36 Issue (3): 82-86    DOI: DOI:10.13523/j.cb.20160312
    
Research Progress of Fibroblast Growth Factor 17
WU Mei-yu1, WANG Hai-jun2, CHENG Ji-liang1, ZHAI Feng3, LI Xiao-kun1,3, JIANG Chao1,3
1. Wenzhou Medical University, Wenzhou 325035, China;
2. Department of Pathology, Xinxiang Medical University, Xinxiang 453003, China;
3. Bioreactor with the Drug Development Project of the Ministry of Education Research Center, Jilin Agricultural University, Changchun 130118, China
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Abstract  

Fibroblast growth factor-17 (FGF17) is one of the fibroblast growth factor (FGF) family members and it makes up FGF8 subfamily along with FGF8 and FGF18. It is an important role in embryo and acts predominantly on multiple tissues and organs. Current evidence suggests that FGF17 is not only involved in the development of brain and neurogenesis, but also participate in many other biological processes, including developmental skeleton and arteries and cancer. The following review summarizes the current knowledge on FGF17 with special emphasis on its characteristics and functions on development of embryo, nervous system, cancer and so on.



Key wordsEmbryo development      FGF17      Nervous system      Cancer     
Received: 26 October 2015      Published: 19 November 2015
ZTFLH:  Q819  
Cite this article:

WU Mei-yu, WANG Hai-jun, CHENG Ji-liang, ZHAI Feng, LI Xiao-kun, JIANG Chao. Research Progress of Fibroblast Growth Factor 17. China Biotechnology, 2016, 36(3): 82-86.

URL:

https://manu60.magtech.com.cn/biotech/DOI:10.13523/j.cb.20160312     OR     https://manu60.magtech.com.cn/biotech/Y2016/V36/I3/82

[1] Armelin H A. Pituitary extracts and steroid hormones in the control of 3T3 cell growth. Proceedings of the National Academy of Science of the United States of America, 1973, 70(9): 2702-2706.
[2] Ornitz D M, Itoh N. The fibroblast growth factor signaling pathway. Wiley Interdiscip Rev Dev Biol, 2015, 4(3): 215-266.
[3] Hoshikawa M, Ohbayashi N, Yonamine A, et al. Structure and expression of a novel fibroblast growth factor, FGF-17, preferentially expressed in the embryonic brain. Biochemical and Biophysical Research Communications, 1998, 244(1): 187-191.
[4] Ford-Perriss M, Abud H, Murphy M. Fibroblast growth factors in the developing central nervous system. Clinical and Experimental Pharmacology and Physiology, 2001, 28(7): 493-503.
[5] Xu J, Lawshe A, MacArthur C A, et al. Genomic structure, mapping, activity and expression of fibroblast growth factor 17. Mechanisms of Development, 1999, 83(1): 165-178.
[6] Zanni G, Barresi S, Travaglini L, et al. FGF17, a gene involved in cerebellar development, is downregulated in a patient with Dandy-Walker malformation carrying a de novo 8p deletion. Neurogenetics, 2011, 12(3): 241-245.
[7] Katoh M, Katoh M. Comparative genomics on FGF8, FGF17, and FGF18 orthologs. International Journal Of Molecular Medicine, 2005, 16(3): 493-496.
[8] Itoh N, Ornitz D M. Functional evolutionary history of the mouse Fgf gene family. Developmental Dynamics, 2008, 237(1): 18-27.
[9] 时小燕,郭靓.成纤维细胞生长因子家族:生物学特性,病理生理学作用及相关治疗方法.国际药学研究杂志,2009,36(5):376-379. Shi X Y, Guo L. Fibroblast growth factor family: biological characteristics, pathophysiological role and related treatment methods. Journal of International Pharmaceutical Research, 2009, 36 (5): 376-379.
[10] Zhang X, Ibrahimi O A, Olsen S K, et al. Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. Journal of Biological Chemistry, 2006, 281(23): 15694-15700.
[11] Ornitz D M, Xu J, Colvin J S, et al. Receptor specificity of the fibroblast growth factor family. Journal of Biological Chemistry, 1996, 271(25): 15292-15297.
[12] Spivak-Kroizman T, Lemmon M A, Dikic I, et al. Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation. Cell, 1994, 79(6): 1015-1024.
[13] Yayon A, Klagsbrun M, Esko J D, et al. Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor. Cell, 1991, 64(4): 841-848.
[14] Mohammadi M, Olsen S K, Ibrahimi O A. Structural basis for fibroblast growth factor receptor activation. Cytokine and Growth Factor Reviews, 2005, 16(2): 107-137.
[15] Ornitz D M. FGFs, heparan sulfate and FGFRs: complex interactions essential for development. Bioessays, 2000, 22(2): 108-112.
[16] Ornitz D M, Yayon A, Flanagan J G, et al. Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells. Molecular and Cellular Biology, 1992, 12(1): 240-247.
[17] Maruoka Y,Ohbayashi N,Hoshikawa M,et al. Comparison of the expression of three highly related genes,Fgf8,Fgf17 and Fgf18,in the mouse embryo.Mechanisms of Development, 1998, 74(1-2): 175-177.
[18] Cholfin J A, Rubenstein J L. Patterning of frontal cortex subdivisions by Fgf17. Proceedings of the National Academy of Sciences, 2007, 104(18): 7652-7657.
[19] Xu J, Liu Z, Ornitz D M. Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures. Development, 2000, 127(9): 1833-1843.
[20] Yu X, Nieman B J, Sudarov A, et al. Morphological and functional midbrain phenotypes in fibroblast growth factor 17 mutant mice detected by Mn-enhanced MRI. Neuroimage, 2011, 56(3): 1251-1258.
[21] Scearce-Levie K, Roberson E D, Gerstein H, et al. Abnormal social behaviors in mice lacking Fgf17. Genes, Brain and Behavior, 2008, 7(3): 344-354.
[22] Bachler M, Neubüser A. Expression of members of the Fgf family and their receptors during midfacial development. Mechanisms of Development, 2001, 100(2): 313-316.
[23] Polnaszek N, Kwabi-Addo B, Wang J, et al. FGF17 is an autocrine prostatic epithelial growth factor and is upregulated in benign prostatic hyperplasia. The Prostate, 2004, 60(1): 18-24.
[24] Heer R, Douglas D, Mathers M E, et al. Fibroblast growth factor 17 is over-expressed in human prostate cancer. The Journal of Pathology, 2004, 204(5): 578-586.
[25] Gauglhofer C, Sagmeister S, Schrottmaier W, et al. Up-Regulation of the Fibroblast Growth Factor 8 Subfamily in Human Hepatocellular Carcinoma for Cell Survival and Neoangiogenesis. Hepatology, 2011, 53(3): 854-864.
[26] Meijer D, Sieuwerts A M, Look M P, et al.. Fibroblast growth factor receptor 4 predicts failure on tamoxifen therapy in patients with recurrent breast cancer. Endocrine-Related Cancer, 2008, 15(1): 101-111.
[27] Nezu M, Tomonaga T, Sakai C, et al. Expression of the fetal-oncogenic fibroblast growth factor-8/17/18 subfamily in human hematopoietic tumors. Biochemical and Biophysical Research Communications, 2005, 335(3): 843-849.
[28] Krejci P, Krakow D, Mekikian P B, et al. Fibroblast growth factors 1, 2, 17, and 19 are the predominant FGF ligands expressed in human fetal growth plate cartilage. Pediatric Research, 2007, 61(3): 267-272.
[29] Kettunen P, Furmanek T, Chaulagain R, et al. Developmentally regulated expression of intracellular Fgf11-13, hormone-like Fgf15 and canonical Fgf16, -17 and -20 mRNAs in the developing mouse molar tooth. Acta Odontologica Scandinavica, 2011, 69(6): 360-366.
[30] Machado M F, Portela V M, Price C A, et al. Regulation and action of fibroblast growth factor 17 in bovine follicles. Journal of Endocrinology, 2009, 202(3): 347-353.
[31] Miraoui H,Dwyer A A,Sykiotis G P,et al. Mutations in FGF17,IL17RD,DUSP6,SPRY4,and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism. Am J Hum Genet,2013,92(5):725-743.

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