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| Application of Cell-penetrating Peptides in Tumor Targeted Therapy and Disease Diagnosis |
Yu-feng ZHANG,Meng-jia XIE,Shu-lei ZHOU,Ling-ling XU,Tie-jun ZHAO( ) |
| College of Chemistry and Life Sciences, Zhejiang Normal University, Jinhua 321004, China |
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Abstract In recent years, cell-penetrating peptides (CPP) have provided an effective strategy for intracellular delivery of biomolecules in the biomedical field. The application of CPP in cancer treatment and disease diagnosis were focused, mainly focused on its roles and advantages in tumor targeted therapy and medical imaging diagnosis. Meanwhile, according to the characteristics of CPP in drug delivery system, the deficiency of CPP should be improved to expand the possibility of combined drug utility, which has become the research hotspot.CPP and its applications were reviewed, then describes some optimized and improved methods to expand the clinical application of CPP.
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Received: 07 November 2018
Published: 12 July 2019
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Corresponding Authors:
Tie-jun ZHAO
E-mail: tjzhao@zjnu.cn
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