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| Bioinformatics Prediction of microRNAs and Targets from Safflower |
| DONG Yuan-yuan1,2, LI Hai-yan2, LI Xiao-kun1,2, YANG Shu-lin 1 |
1. School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China;
2. Engineering Research Center of Bioreactor and Pharmaceutical Development, Ministry of Education, Jilin Agricultural University, Changchun 130118, China |
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Abstract miRNA is a kind of noncoding RNA in post regulation, plant miRNA come from RNA precursor with hairpin structure. Mature miRNA interacts with a member of the ARGONAUTE protein complexes. The protein complexes are typically located in the 3' untranslated region of mRNAs leading to inhibition of gene expression. miRNAs were typically conserved in plants. miRNAs sequences database were matched with EST sequences of safflower, 109 safflower microRNAs and 385 targets were predicted out. miRNA target genes from safflower were predicted to encode transcription factors or proteins that regulate cell growth and development, signaling, and metabolism.
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Received: 25 May 2012
Published: 25 October 2012
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