[1] Prokhortchouk E, Defossez P A. The cell biology of DNA methylation in mammals. Biochim Biophys Acta, 2008, 1783(11): 2167-2173.
[2] Shiota K, Kogo Y, Ohgane J, et al. Epigenetic marks by DNA methylation specific to stem, germ and somatic cells in mice. Genes Cells, 2002, 7(9): 961-969.
[3] Eckhardt F, Lewin J, Cortese R, et al. DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet, 2006, 38(12): 1378-1385.
[4] Illingworth R, Kerr A, Desousa D, et al. A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol, 2008, 6(1): e22.
[5] Sørensen A L, Jacobsen B M, Reiner A H, et al. Promoter DNA methylation patterns of differentiated cells are largely programmed at the progenitor stage. Mol Biol Cell, 2010, 21(12): 2066-2077.
[6] Fabbri M, Garzon R, Cimmino A, et al. MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci USA, 2007, 104 (40): 15805-15810.
[7] Garzon R, Liu S, Fabbri M, et al. MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood, 2009, 113(25): 6411-6418.
[8] Nguyen T, Kuo C, Nicholl M B, et al. Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma. Epigenetics, 2011, 6(3): 388-394.
[9] Sandhu R, Rivenbark A G, Mackler R M, et al. Dysregulation of microRNA expression drives aberrant DNA hypermethylation in basal-like breast cancer. Int J Oncol, 2014, 44(2): 563-572.
[10] Starlard-Davenport A, Kutanzi K, Tryndyak V, et al. Restoration of the methylation status of hypermethylated gene promoters by microRNA-29b in human breast cancer: A novel epigenetic therapeutic approach. J Carcinog, 2013, 12: 15-31.
[11] Zheng J, Wu C, Lin Z, et al. Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation -a novel mechanism suppressing liver fibrosis. FEBS J, 2014, 281(1): 88-103.
[12] Qin H, Zhu X, Liang J, et al. MicroRNA-29b contributes to DNA hypomethylation of CD4+ T cells in systemic lupus erythematosus by indirectly targeting DNA methyltransferase 1. J Dermatol Sci, 2013, 69(1): 61-67.
[13] Morita S, Horii T, Kimura M, et al. miR-29 represses the activities of DNA methyltransferases and DNA demethylases. Int J Mol Sci, 2013, 14(7): 14647-14658.
[14] Huang J, Wang Y, Guo Y, et al. Down-regulated microRNA-152 induces aberrant DNA methylation in hepatitis B virus-related hepatocellular carcinoma by targeting DNA methyltransferase 1. Hepatology, 2010, 52(1): 60-70.
[15] Wang Y S, Chou W W, Chen K C, et al. MicroRNA-152 mediates DNMT1-regulated DNA methylation in the estrogen receptor α gene. PLoS One, 2012, 7(1): e30635.
[16] Ng E K, Li R, Shin V Y, et al. MicroRNA-143 is downregulated in breast cancer and regulates DNA methyltransferases 3A in breast cancer cells. Tumour Biol, 2014, 35(3): 2591-2598.
[17] Zhao S, Wang Y, Liang Y, et al. MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1. Arthritis Rheum, 2011, 63(5): 1376-1386.
[18] Pan W, Zhu S, Yuan M, et al. MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1. J Immunol, 2010, 184(12): 6773-6781.
[19] Chen B F, Gu S, Suen Y K, et al. microRNA-199a-3p, DNMT3A, and aberrant DNA methylation in testicular cancer. Epigenetics, 2014, 9(1): 119-128.
[20] Wang H, Wu J, Meng X, et al. MicroRNA-342 inhibits colorectal cancer cell proliferation and invasion by directly targeting DNA methyltransferase 1. Carcinogenesis, 2011, 32(7): 1033-1042.
[21] Zhang Z, Tang H, Wang Z, et al. MiR-185 targets the DNA methyltransferases 1 and regulates global DNA methylation in human glioma. Mol Cancer, 201, 10: 124-139.
[22] Chavali V, Tyagi S C, Mishra P K. MicroRNA-133a regulates DNA methylation in diabetic cardiomyocytes. Biochem Biophys Res Commun, 2012, 425(3): 668-672.
[23] Song K, Han C, Zhang J, et al. Epigenetic regulation of miR-122 by PPARγ and hepatitis B virus X protein in hepatocellular carcinoma cells. Hepatology, 2013, 58(5):1681-1692.
[24] Xing T J, Xu H T, Yu W Q, et al. Methylation regulation of liver-specific microRNA-122 expression and its effects on the proliferation and apoptosis of hepatocellular carcinoma cells. Genet Mol Res, 2013, 12(3): 3588-3597.
[25] Chen X, Zhang L, Zhang T, et al. Methylation-mediated repression of microRNA 129-2 enhances oncogenic SOX4 expression in HCC. Liver Int, 2013, 33(3): 476-486.
[26] He Y, Cui Y, Wang W, et al. Hypomethylation of the hsa-miR-191 locus causes high expression of hsa-mir-191 and promotes the epithelial-to-mesenchymal transition in hepatocellular carcinoma. Neoplasia, 2011, 13(9): 841-853.
[27] Datta J, Kutay H, Nasser M W, et al. Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis. Cancer Res, 2008, 68(13): 5049-5058.
[28] Geng J, Luo H, Pu Y, et al. Methylation mediated silencing of miR-23b expression and its role in glioma stem cells. Neurosci Lett, 2012, 528(2):185-189.
[29] Wong K Y, Yim R L, So C C, et al. Epigenetic inactivation of the MIR34B/C in multiple myeloma. Blood, 2011, 118(22): 5901-5904.
[30] Toyota M, Suzuki H, Sasaki Y, et al. Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res, 2008, 68(11): 4123-4132.
[31] Grady W M, Parkin R K, Mitchell P S, et al. Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer. Oncogene, 2008, 27(27): 3880-3888.
[32] Tang J T, Wang J L, Du W, et al. MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer. Carcinogenesis, 2011, 32(8): 1207-1215.
[33] Takahashi Y, Iwaya T, Sawada G, et al. Up-regulation of nek2 by microrna-128 methylation is associated with poor prognosis in colorectal cancer. Ann Surg Oncol, 2014, 21(1): 205-212.
[34] Yamada N, Noguchi S, Kumazaki M, et al. Epigenetic regulation of microRNA-128a expression contributes to the apoptosis-resistance of human T-cell leukaemia Jurkat cells by modulating the expression of Fas-associated protein with death domain (FADD). Biochim Biophys Acta, 2013, 1843(3): 590-602.
[35] Dou L, Zheng D, Li J, et al. Methylation-mediated repression of microRNA-143 enhances MLL-AF4 oncogene expression. Oncogene, 2012, 31(4): 507-517.
[36] Gao X N, Lin J, Li Y H, et al. MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia. Oncogene, 2011, 30(31): 3416-3428.
[37] Bueno M J, Pérez de Castro I, Gómez de Cedrón M, et al. Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression. Cancer Cell, 2008, 13(6): 496-506.
[38] Wang P, Chen L, Zhang J, et al. Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1. Oncogene, 2014, 33(4): 514-524.
[39] Hanoun N, Delpu Y, Suriawinata A A, et al. The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic carcinogenesis. Clin Chem, 2010, 56(7): 1107-1118.
[40] Suzuki H, Yamamoto E, Nojima M, et al. Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect. Carcinogenesis, 2010, 31(12): 2066-2073.
[41] Lei H, Zou D, Li Z, et al. MicroRNA-219-2-3 Pfunctions as a tumor suppressor in gastric cancer and is regulated by DNA methylation. PLoS One, 2013, 8(4): e60369.
[42] Xu L, Wang F, Xu X F, et al. Down-regulation of miR-212 expression by DNA hypermethylation in human gastric cancer cells. Med Oncol, 2011, 28(Suppl 1):189-196.
[43] Suh S O, Chen Y, Zaman M S, et al. MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer. Carcinogenesis, 2011, 32(5): 772-778.
[44] Chu M, Chang Y, Li P, et al. Androgen receptor is negatively correlated with the methylation-mediated transcriptional repression of miR-375 in human prostate cancer cells. Oncol Rep, 2014, 31(1): 34-40.
[45] Shimizu T, Suzuki H, Nojima M, et al. Methylation of a panel of microRNA genes is a novel biomarker for detection of bladder cancer. Eur Urol, 2013, 63(6): 1091-1100.
[46] Gebauer K, Peters I, Dubrowinskaja N, et al. Hsa-mir-124-3 CpG island methylation is associated with advanced tumours and disease recurrence of patients with clear cell renal cell carcinoma. Br J Cancer, 2013, 108(1): 131-138.
[47] Alvarado S, Wyglinski J, Suderman M, et al. Methylated DNA binding domain protein 2 (MBD2) coordinately silences gene expression through activation of the MicroRNA hsa-mir-496 promoter in breast cancer cell line. PLoS One, 2013, 8(10): e74009.
[48] Yu F, Jiao Y, Zhu Y, et al. MicroRNA 34c gene down-regulation via DNA methylation promotes self-renewal and epithelial-mesenchymal transition in breast tumor-initiating cells. J Biol Chem, 2012, 287(1): 465-473.
[49] Skrn M I, Barøy T, Stratford E W, et al. Epigenetic regulation and functional characterization of MicroRNA-142 in mesenchymal cells. PLoS One, 2013, 8(11): e79231.
[50] Pieraccioli M, Imbastari F, Antonov A, et al. Activation of miR200 by c-Myb depends on ZEB1 expression and miR200 promoter methylation. Cell Cycle, 2013, 12(14): 2309-2320.
[51] Diao Y, Guo X, Jiang L, et al. miR-203, a tumor suppressor frequently down-regulated by promoter hypermethylation in Rhabdomyosarcoma. J Biol Chem, 2014, 289(1): 529-539.
[52] Yang C, Cai J, Wang Q, et al. Epigenetic silencing of miR-130b in ovarian cancer promotes the development of multidrug resistance by targeting colony-stimulating factor 1. Gynecol Oncol, 2012, 124(2): 325-334.
[53] Minor J, Wang X, Zhang F, et al. Methylation of microRNA-9 is a specific and sensitive biomarker for oral and oropharyngeal squamous cell carcinomas. Oral Oncol, 2012, 48(1): 73-78.
[54] Saito J, Hirota T, Furuta S, et al. Association between DNA methylation in the miR-328 5'-flanking region and inter-individual differences in miR-328 and BCR Pexpression in human placenta. PLoS One, 2013, 8(8): e72906.
[55] Zhu A, Xia J, Zuo J, et al. MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in gastric cancer. Med Oncol, 2012, 29(4): 2701-2709.
[56] Tsuruta T, Kozaki K, Uesugi A, et al. miR-152 is a tumor suppressor microRNA that is silenced by DNA hypermethylation in endometrial cancer. Cancer Res, 2011, 71(20): 6450-6462.
[57] Chen Y, Shin B C, Thamotharan S, et al. Differential methylation of the micro-RNA 7b gene targets postnatal maturation of murine neuronal Mecp2 gene expression. Dev Neurobiol, 2014, 74(4): 407-425.
[58] Muraoka T, Soh J, Toyooka S, et al. The degree of microRNA-34b/c methylation in serum-circulating DNA is associated with malignant pleural mesothelioma. Lung Cancer, 2013, 82(3): 485-490.
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