中国生物工程杂志

The human intestinal microbiome plays an important role in maintaining human health and the occurrence and development of diseases. The world is faced with some serious infectious diseases such as the novel coronavirus epidemic, and foodborne diseases, pathogenic drug-resistant “superbugs” and other problems are becoming more serious, threatening human health. Therefore, it is of great practical significance to use patent big data to carry out the analysis of the research and development (R&D) situation of the global intestinal microecology industry based on the patent map, make a preliminary judgment on the development direction of the intestinal microecology industry, and clarify the R&D hotspots. Based on the patent map, this paper focuses on analyzing the patent application trend, disclosure of applicants’ nations, inventor, technical composition, R&D hotspots, core patent technology path evolution trend and competitive influence of key institutions from 2011 to 2021 and from the dimensions of patent management map and patent technology map. The study found that the number of patent applications in the global intestinal microecology industry showed a gradual and rapid growth trend, reaching the second peak in 2020, and will continue to increase rapidly in the future. China is the country with the highest proportion of patent applications, acceptance and disclosure, and the top 10 first inventors (designers) in terms of application volume are mainly from China. The field of bacteroides|bacteria is a global R&D hotspot, the R&D hotspots of various countries have their own merits, and the overall complementary advantages have been formed.