China Biotechnology

Isolation and Characterization of an Efficient Strain of Human Intestinal Origin for Uric Acid Degradation

XU Tiancheng, CHEN Biao, CUI Xiaoyi, YE Li

China Biotechnology, 2025, 45(12): 1-13. DOI: 10.13523/j.cb.202506010

抗菌药物	测定值/mm	判断标准(抑制圈直径/mm)			敏感性
抗菌药物	测定值/mm	耐药(R)	中度敏感(I)	高度敏感(S)	敏感性
氨苄西林	17	≤15	16~22	≥23	I
羧苄西林	31	≤22	23~29	≥30	S
哌拉西林	28	≤23	24~30	≥31	I
头孢唑啉	26	≤20	21~27	≥28	I
头孢呋辛	26	≤19	20~22	≥23	S
头孢他啶	30	≤24	25~32	≥33	I
头孢曲松	34	≤28	29~35	≥36	I
头孢哌酮	32	≤27	28~34	≥35	I
庆大霉素	25	≤18	19~26	≥27	I
环丙沙星	43	≤29	30~40	≥41	S

Table 2 nf-5 drug sensitivity test results

Other figure/table from this article

Fig.1 Transparent circle of strain nf-5 cultured on a uric acid plate for 24 hours
Fig.2 Uric acid metabolism effect of reselected strain
Fig.3 Colony morphology of strain nf-5
Fig.4 Gram staining microscopy image
Fig.5 Phylogenetic tree based on 16S rRNA gene sequence
Table 1 IMVC biochemical identification results and biological significance of strain nf-5
Fig.6 The impact of different sterilization methods on the concentration of uric acid in liquid medium
Fig.7 OD₆₀₀ values under different dissolved oxygen conditions
Fig.8 Effect of dissolved oxygen conditions on uric acid metabolism of strain nf-5
Fig. 9 Uric acid concentration-time curve under different dissolved oxygen conditions
Fig.10 OD₆₀₀-time curve under different dissolved oxygen conditions
Fig.11 OD₆₀₀ values of nf-5 under different nutritional conditions at 18 hours
Fig.12 Changes in uric acid concentration within 18 hours under different nutritional conditions
Fig.13 Changes in uric acid concentration within 24 hours under different glucose concentrations
Fig.14 OD₆₀₀-time curve under different glucose concentrations
Fig.15 Uric acid concentration-time curve under different glucose concentrations
Fig.16 The impact of osmotic pressure regulation on uric acid degradatio
Fig.17 Changes in uric acid concentration within 18 hours at different glycerol concentrations