研究报告 |
|
|
|
|
斑马鱼tbx2b调控心脏房室间隔发育的功能研究* |
赵霞1,2,3,朱哲1,2,3,祖尧1,2,3,**() |
1 上海海洋大学 科技部海洋生物科学国际联合研究中心 上海 201306 2 上海海洋大学 水产种质资源发掘与利用教育部重点实验室 上海 201306 3 上海海洋大学 国家水生动物病原库 上海 201306 |
|
tbx2b Affects Atrioventricular Canal Development in Zebrafish |
ZHAO Xia1,2,3,ZHU Zhe1,2,3,ZU Yao1,2,3,**() |
1 International Research Center for Marine Biosciences, Ministry of Science and Technology, College of Fisheries and Life Sciences, Shanghai Ocean University, Shanghai 201306, China 2 Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, College of Fisheries and Life Sciences, Shanghai Ocean University, Shanghai 201306, China 3 National Pathogen Collection Center for Aquatic Animals, Shanghai Ocean University, Shanghai 201306, China |
[1] |
Hoffman J I E, Kaplan S. The incidence of congenital heart disease. Journal of the American College of Cardiology, 2002, 39(12):1890-1900.
pmid: 12084585
|
[2] |
Liu Y J, Chen S, Zühlke L, et al. Global birth prevalence of congenital heart defects 1970-2017: updated systematic review and meta-analysis of 260 studies. International Journal of Epidemiology, 2019, 48(2):455-463.
doi: 10.1093/ije/dyz009
|
[3] |
Pang S C, Liu Y M, Zhao Z Q, et al. Novel and functional sequence variants within the TBX2 gene promoter in ventricular septal defects. Biochimie, 2013, 95(9):1807-1809.
doi: 10.1016/j.biochi.2013.05.007
|
[4] |
Liu N, Schoch K, Luo X, et al. Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder. Human Molecular Genetics, 2018, 27(14):2454-2465.
doi: 10.1093/hmg/ddy146
|
[5] |
Verhoeven M C, Haase C, Christoffels V M, et al. Wnt signaling regulates atrioventricular canal formation upstream of BMP and Tbx2. Birth Defects Research Part A: Clinical and Molecular Teratology, 2011, 91(6):435-440.
doi: 10.1002/bdra.20804
|
[6] |
Bakkers J. Zebrafish as a model to study cardiac development and human cardiac disease. Cardiovascular Research, 2011, 91(2):279-288.
doi: 10.1093/cvr/cvr098
pmid: 21602174
|
[7] |
Gut P, Reischauer S, Stainier D Y R, et al. Little fish, big data: zebrafish as a model for cardiovascular and metabolic disease. Physiological Reviews, 2017, 97(3):889-938.
doi: 10.1152/physrev.00038.2016
|
[8] |
Liu J D, Stainier D Y R. Zebrafish in the study of early cardiac development. Circulation Research, 2012, 110(6):870-874.
doi: 10.1161/CIRCRESAHA.111.246504
|
[9] |
Mosimann C, Panáková D, Werdich A A, et al. Chamber identity programs drive early functional partitioning of the heart. Nature Communications, 2015, 6(1):1-10.
|
[10] |
Olson E N. Gene regulatory networks in the evolution and development of the heart. Science, 2006, 313(5795):1922-1927.
pmid: 17008524
|
[11] |
Clowes C, Boylan M G S, Ridge L A, et al. The functional diversity of essential genes required for mammalian cardiac development. Genesis, 2014, 52(8):713-737.
doi: 10.1002/dvg.v52.8
|
[12] |
Harrelson Z, Kelly R G, Goldin S N, et al. Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart development. Development, 2004, 131(20):5041-5052.
pmid: 15459098
|
[13] |
Shirai M, Imanaka-Yoshida K, Schneider M D, et al. T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgf 2 expression and endocardial cushion formation. PNAS, 2009, 106(44):18604-18609.
doi: 10.1073/pnas.0900635106
|
[14] |
Christoffels V M, Hoogaars W M H, Tessari A, et al. T-box transcription factor Tbx2 represses differentiation and formation of the cardiac chambers. Developmental Dynamics, 2004, 229(4):763-770.
pmid: 15042700
|
[15] |
Camenisch T D, Spicer A P, Brehm-Gibson T, et al. Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme. The Journal of Clinical Investigation, 2000, 106(3):349-360.
doi: 10.1172/JCI10272
|
[16] |
Singh R, Hoogaars W M, Barnett P, et al. Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formation. Cellular and Molecular Life Sciences, 2012, 69(8):1377-1389.
doi: 10.1007/s00018-011-0884-2
|
[17] |
Habets P E M h. Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation. Genes & Development, 2002, 16(10):1234-1246.
doi: 10.1101/gad.222902
|
[18] |
Chapman DL, Garvey N, Hancock S, et al. Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development. Developmental Dynamics, 2010, 206(4):379-390.
doi: 10.1002/(ISSN)1097-0177
|
[19] |
Ribeiro I, Kawakami Y, Büscher D, et al. Tbx2 and Tbx3 regulate the dynamics of cell proliferation during heart remodeling. PLoS One, 2007, 2(4):e398. DOI: 10.1371/journal.pone.0000398.
doi: 10.1371/journal.pone.0000398
|
[20] |
Ma L J, Lu M F, Schwartz R J, et al. Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning. Development, 2005, 132(24):5601-5611.
doi: 10.1242/dev.02156
|
[21] |
Yamada M, Revelli J P, Eichele G, et al. Expression of chick tbx-2, tbx-3, and tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2. Developmental Biology, 2000, 228(1):95-105.
pmid: 11087629
|
[22] |
Just S, Hirth S, Berger I M, et al. The mediator complex subunit Med10 regulates heart valve formation in zebrafish by controlling Tbx2b-mediated Has2 expression and cardiac jelly formation. Biochemical and Biophysical Research Communications, 2016, 477(4):581-588.
doi: 10.1016/j.bbrc.2016.06.088
|
[23] |
Man J, Barnett P, Christoffels V M. Structure and function of the Nppa-Nppb cluster locus during heart development and disease. Cellular and Molecular Life Sciences, 2018, 75(8):1435-1444.
doi: 10.1007/s00018-017-2737-0
|
[24] |
Lagendijk A K, de Angelis J E, et al. Nppa and Nppb act redundantly during zebrafish cardiac development to confine AVC marker expression and reduce cardiac jelly volume. Development, 2018, 145(12). DOI: 10.1242/dev.160739.
doi: 10.1242/dev.160739
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
|
Shared |
|
|
|
|
|
Discussed |
|
|
|
|