疫苗、抗体等多种生物制品的生产依赖动物细胞的规模化培养，而微载体细胞培养技术是一种新兴的贴壁依赖型细胞大规模培养技术。本文简要介绍了细胞发展史，并就微载体系统规模化细胞培养，从微载体和生物反应器的选择、细胞培养方式特别是灌流培养的介绍、细胞代谢与反应器中的生存环境的探讨，以及微载体发展前景的展望等方面进行了论述和讨论。
Cell culture on microcarrier is a new kind of large scale culturing technique, and which is used by many bioproducts, such as vaccine and antibody. In this paper we introduce the history of cell culture briefly, and discuss the selection of the microcarrier and bioreator, described the mode of cultrue, the enviroment in the bioreator, and the prospects of this technique.
张彦鹏. 微载体系统规模化细胞培养研究[J]. 中国生物工程杂志, 2008, 28(专刊): 215-219.
https://manu60.magtech.com.cn/biotech/CN/Y2008/V28/I专刊/215
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