研究报告 |
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高产截短侧耳素担子菌的抗性突变株筛选 |
陈晓丽,张文琦,胡昌华** |
西南大学药学院 现代生物医药研究所 重庆 400716 |
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Resistant Mutant Screening of Pleuromutilin High-producing Clitopilus prunulus |
CHEN Xiao-li,ZHANG Wen-qi,HU Chang-hua |
Institute of Modern Biopharmaceuticals, School of Pharmaceutical Sciences, Southwest University, Chongqing 400716,China |
[1] 邹懿, 黄宇琪, 胡昌华.截短侧耳素及其衍生物的研究进展. 中国抗生素杂志, 2009, 34(2): 6568. Zou Y, Huang Y Q, Hu C H. Chinese Journal of Antibiotics, 2009,34(2): 6568.
[2] Hu C H, Zou Y. Mutilins derivatives from veterinary to humanused antibiotics.Medicinal Chemistry,2009,9(12):13971406.
[3] Kavanagh F, Hervey A, Robbins W J. Antibiotic substances from Basidiomycetes: VIII. Pleurotus Multilus (Fr.) Sacc. and Pleurotus Passeckerianus Pilat. Proc Natl Acad Sci U S A, 1951, 37(9): 570574.
[4] Hartley A J, Collins C M. Investigating pleuromutilinproducing Clitopilus species and related basidiomycetes. FEMS Microbiol Letters, 2009, 297(1): 2430.
[5] Papa I A, Zulaybar T O, Raymundo A K . Increasing pleuromutilin activity of Clitopilus passeckerianus by chemical mutagenesis and improvement of production medium. Phil Agr Sci,2006, 89(1):2033.
[6] Beltrametti F, Rossi R, Selva E, et al. Antibiotic production improvement in the rare actinomycete Planobispora rosea by selection of mutants resistant to the aminoglycosides streptomycin and gentamycin and to rifamycin. Journal of Industrial Microbiology & Biotechnology 2006,33(4): 283288.
[7] Hu H F, Ochi K. Novel approach for improving the productivity of antibioticproducing strains by inducing combined resistant mutations. Appled and Environmental Microbiology, 2001, 67(4): 18851892.
[8] 赵凯, 周东坡, 平文祥,等. 产紫杉醇菌株原生质体诱变育种的研究. 生物工程学报, 2005, 21(5): 848851. Zhao K, Zhou D P, Ping W X et al. Journal of Biological Engineering, 2005, 21(5): 848851.
[9] Ozaki H, Ishihara M, Kida T, et al.. Mycophenolic acid production by drugresistant and methionine or glutamicacid requiring mutants of penicillium brevicompactum. Agriculture Biology and Chemistry, 1987, 51(9): 25092514.
[10] 黄宇琪, 张怡,胡昌华. 截短侧耳素产生菌的鉴定及发酵培养基初筛. 四川大学学报(自然科学版), 2008,45(3): 699702. Huang Y Q, Zhang Y, Hu C H.Journal of Sichuan University,2008,45(3):699702.
[11] Hu C H, Zou Y, Zhao W T. Effect of soybean oil on the production of mycelial biomass and pleuromutilin in the shake?ask culture of Pleurotus mutilis. World Journal of Microbiology and Biotechnology, 2009, 25(10): 17051711.
[12] Shang F, Wen S, Wang X, et al. Effect of nitrogen limitation on the ergosterol production by fedbatch culture of Saccharomyces cerevisiae. Journal of Biotechnology, 2006, 122(3): 285292.
[13] 赵文婷,邹懿,胡昌华. 微生物菌种改良的新方法新策略. 生物工程学报,2009, 25(6): 801805. Zhao W T, Zou Y, Hu C H. Journal of Biological Engineering, 2009, 25(6): 801805.
[14] Justin R N. Novel links between antibiotic resistance and antibiotic production. Journal of Bacteriology, 2007, 189(10): 36833685.
[15] Ochi K. From microbial differentiation to ribosome engineering. Bioscience Biotechnology and Biochemistry, 2007, 71(6): 13731386.
[16] Shobayashi M, Mukai N, Iwashita K, et al. A new method for isolation of Sadenosylmethionine (SAM)accumulating yeast. Applied Microbial and Cell Physiology, 2006,69: 704710. |
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