研究报告 |
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PEG-重组酵母尿酸酶结合物的基本特性研究 |
赵兴秀1**何义国1姚兴川2 杜林方2孟延发2 |
1.四川理工学院 自贡 643000
2.四川大学生命科学学院 成都 610064 |
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Study on General Properties of PEGylated Recombinant Uricase |
ZHAO Xing-xiu1,HE Yi-guo1,YAO Xing-chuan2,DU Lin-fang2,MENG Yan-fa2 |
1.Sichuan University of Science & Engineering,Zigong 643000,China
2.College of Life Science, Sichuan University,Chengdu 610064, China |
[1] |
Oda M, Satta Y, Takenaka O, et al. Loss of urate oxidase activity in hominoids and its evolutionary implications. Mol Biol Evol, 2002, 19(5): 640~653
|
[2] |
Baeksgaard L, Sorensen J B. Acute tumor lysis syndrome in solid tumorsa case report and review of the literature. Cancer Chemother Pharmacol, 2003, 51(3): 187~192
|
[3] |
Bardin T. Current management of gout in patients unresponsive or allergic to allopurinol. Joint Bone Spine, 2004, 71(6): 481~485
|
[4] |
Nuki G. Treatment of crystal arthropathyhistory and advances. Rheum Dis Clin North Am, 2006, 32(2): 333~357
|
[5] |
才蕾, 高向东, 朱姝, 等. 聚乙二醇修饰尿酸酶的研究. 中国药科大学学报, 2008, 39(6): 557~562 Cai L, Gao X D, Zhu S, et al. Journal of China Pharmaceutical University, 2008, 39(6): 557~562
|
[6] |
Toyobo co. lid. Toyobo enzymes. Japan: Biochemical operations department, 1996.171
|
[7] |
汪家政, 范明. 蛋白质技术手册. 北京: 科学出版社, 2002.38~50 Wang J Z, Fan M.Protein Technical Manual. Beijing: Science Press, 2002.38~50
|
[8] |
Bomalaski J S, Holtsberg F W, Ensor C M, et al. Uricase formulated with polyethylene glycol (uricasePEG 20): biochemical rationale and preclinical studies. J Rheumatol, 2002, 29(9): 1942~1949
|
[9] |
Liao F, Zhu X Y, Wang Y M, et al. The comparison of the estimation of enzyme kinetic parameters by fitting reaction curve to the integrated MichaelisMenten rate equations of different predictor variables. J Biochem Biophys Methods, 2005, 62(1): 13~24
|
[10] |
Davis S, Park Y K, Abuchowski A, et al. Hypouricaemic effect of polyethyleneglycol modified urate oxidase. Lancet, 1981, 2(8241): 281~283
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