Cre/loxP系统是源于P1噬菌体的一个DNA重组体系，具有位点特异、时期特异、组织特异和高效重组的特点,它为转基因生物工程研究提供有力工具。概述了Cre/loxP系统的组成、结构、作用方式、机制、特点及其在酵母中的应用。
Cre/loxP system is a recombinase system which origins from bacteriophage P1.It has become an important tool for genetically modified bioengineering because it is time-specific, tissue- specific，site-specific and efficient recombination.In this paper, the recombinant characteristics of the Cre/loxP system, the compositions and structure of cre recombinase，recombination mechanism and application in yeast, is reviewed.
和东芹,肖冬光,吕烨. Cre/ lox P系统介导的基因重组及其在酵母中的应用[J]. 中国生物工程杂志, 2008, 28(专刊): 46-49.
. Cre/ loxP System-mediated Gene Recombination and It's Application in Yeast. China Biotechnology, 2008, 28(专刊): 46-49.
https://manu60.magtech.com.cn/biotech/CN/ 或 https://manu60.magtech.com.cn/biotech/CN/Y2008/V28/I专刊/46
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