中国生物工程杂志

It introduces the physico-chemical chemical and physical propertiyes of itaconic acid. There are Ttwo main production methods to produceof itaconic acid，which are , chemical and biological fermentation. Many researches have been focus on choices of raw materials and strains, application of deep fermentation and immobilization technology in fermentation process, comparison of re-crystallization ,ion exchange resins , organic solvent in the extraction process in the microbiological fermentation.Focused on the method of microbial fermentation introducing. Research on raw materials, fermentation bacteria choice, fermentation process such as deep fermentation, immobilization technology. The comparison of three extraction technology, such as re-crystallization process, ion resins exchange technology, organic solvent extraction method. The production status of itaconic acid and production capacity of all componies in domestic and international market, their is production capacity are overviewed. Besides, the products of itaconic acid and its derivatives products in the new highly efficiency efficient deodorant, cleaning industry, adhesives and other industrial applications araree detailed summarized. The author also estimates the market application prospects of itaconic acid. was also forecasted.