| 研究报告 |
|
|
|
|
| 表达轮状病毒nsp4基因重组腺病毒的构建与免疫评价 |
| 谢力1,2, 王晓囡1, 李杨1, 严敏1, 曹颖1, 李鸿钧1, 孙茂盛1 |
1. 中国医学科学院/北京协和医学院 医学生物学研究所 云南省重大传染病疫苗研发重点实验室 昆明 650118;
2. 昆明学院医学院 昆明 650214 |
|
| Construction and Immunogenicity of a Recombinant Adenovirus Expressing NSP4 of Group A Rotavirus |
| XIE Li1,2, WANG Xiao-nan1, LI Yang1, YAN Min1, CAO Yin1, LI Hong-jun1, SUN Mao-sheng1 |
1. Institute of Medical Biology, Chinese Academy of Medical Sciences/Peking Union Medical College; Yunnan Key laboratory of Vaccine Research & Development on Severe Infections Diseases, Kunming 650118, China;
2. Medical School of Kunming University, Kunming 650214, China |
引用本文:
谢力, 王晓囡, 李杨, 严敏, 曹颖, 李鸿钧, 孙茂盛. 表达轮状病毒nsp4基因重组腺病毒的构建与免疫评价[J]. 中国生物工程杂志, 2014, 34(2): 1-6.
XIE Li, WANG Xiao-nan, LI Yang, YAN Min, CAO Yin, LI Hong-jun, SUN Mao-sheng. Construction and Immunogenicity of a Recombinant Adenovirus Expressing NSP4 of Group A Rotavirus. China Biotechnology, 2014, 34(2): 1-6.
链接本文:
https://manu60.magtech.com.cn/biotech/CN/10.13523/j.cb.20140201
或
https://manu60.magtech.com.cn/biotech/CN/Y2014/V34/I2/1
|
| [1] Orenstein E W, Fang Z Y, Xu J, et a1. The epidemiology and burden of rotavirus in China: a review of the literature from 1983 to 2005. Vaccine, 2007,25(3): 406-413.
[2] Fang Z Y, Wang B, Kilgore P E, et al. Sentinel hospital surveillance for rotavirus diarrhea in the Pepple's Republic of China, August 2001-July 2003. J Infect Dis, 2005,192(Suppl 1):S94-S99.
[3] Dennehy P H. Rotavirus vaccines: an overview. Clin Microbiol Rev, 2008,21(1):198-208.
[4] Greenberg H B, Estes M K. Rotaviruses: from pathogenesis to vaccination. Gastroenterology, 2009,136(6):1939-1951.
[5] Bernstein D I. Rotavirus overview. Pediatr Infect Dis J, 2009,28(3 Suppl):50-53.
[6] Lin S L, Tian P. Detailed computational analysis of a comprehensive set of group A rotavirus NSP4 proteins. Virus Genes, 2003, 26(3):271-282
[7] Rotavirus surveillance-worldwide, 2001-2008. MMWR Morb Mortal Wkly Rep, 2008,57(46):1255-1257.
[8] Gorrell R J, Bishop R F. Homotypic and heterotypic serum neutralizing antibody response to rotavirus proteins following natural primary infection and reinfection in children. J Med Virol, 1999,57(2):204-211.
[9] Parashar U D, Gibson C J, Bresse J S, et al. Rotavirus and severe childhood diarrhea. Emerg Infect Dis, 2006,12(2):304306.
[10] Ball J M, Tian P, Zeng C Q, et al. Age-dependent diarrhea induced by a rotaviral nonstructural glycoprotein. Science, 1996,272(5258):101-104.
[11] Diaz Y, Pena F, Aristimuno O C, et al. Dissecting the Ca2+ entry pathways induced by rotavirus infection and NSP4-EGF Pexpression in Cos-7 cells. Virus Res, 2012,167(2):285-296.
[12] Hyser J M, Utama B, Crawford S E, et al. Activation of the endoplasmic reticulum calcium sensor STIM1 and store-operated calcium entry by rotavirus requires NSP4 viroporin activity. J Virol, 2013,87(24):13579-13588.
[13] Silvestri L S, Tortorici M A, Vasquez-Del Carpio R, et al. Rotavirus glycoprotein NSP4 is a modulator of viral transcription in the infected cell. J Virol, 2005,79(24):15165-15174.
[14] van Dijk K W, Kypreos K E, Fallaux F J, et al. Adenovirus-mediated gene transfer. Methods Mol Biol, 2011,693:321-343.
[15] 王大燕, 王健伟, 王彦斌,等.轮状病毒NSP4基因在非复制型腺病毒载体中的表达及免疫活性.世界华人消化杂志,2006,14(9):858-862. Wang D Y, Wang J W, Wang Y B, et al. Generation and Immunogenicity of a recombinant replication-incompetent adenovirus expressing human rotavirus NSP4 protein. World Chinese Journal of Digestology, 2006,14(9):858-862.
[16] Azevedo M P, Vlasova A N, Saif L J. Human rotavirus virus-like particle vaccines evaluated in a neonatal gnotobiotic pig model of human rotavirus disease. Expert Rev Vaccines, 2013,12(2):169-181. |
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
| |
Shared |
|
|
|
|
| |
Discussed |
|
|
|
|
