中国生物工程杂志

［1］ Singaraja R, Visscher H, James E,et al. Specific mutations in ABCA1 have discrete effects on ABCA1 function and lipid phenotypes both in vivo and in vitro. Circ Res,2006,99(4):389397. 
［2］ SantamarinaFojo S, Peterson K, Knapper C.Complete genomic sequence of the human ABCA1 gene: Analysis of the human and mouse ATPbinding cassette A promoter.PNAS,2000,97(14): 79877992. 
［3］ 杨丽, 杨磊, 曾妍,等. Hela 细胞转染表达ABCA1 对其抗砷性的影响. 石河子大学学报(自然科学版),2007,25(6):661663. Yang L,Yang L,Zeng Y,et al.Journal of Shihezi University(Natural Science) ,2007,25(6):661663. 
［4］ 仙玲玲，杨磊 ，罗星，等.长期低剂量诱导法培养人体抗砷细胞株的研究. 中国地方病学杂志，2005,24(2):143145. Xian L L,Yang L, Luo X,et al. Chin J Endemiol,2005,24(2):143145. 
［5］ Singaraja R, Brunham L, Visscher H,et al. Efflux and Atherosclerosis: The Clinical and biochemical impact of variations in the ABCA1 gene. Arterioscler Thromb Vasc Biol, 2003,23(8):13221332. 
［6］ Valleio A , Pogulis R,Pease L. In vitro synthesis of novel genes:mutagenesis and recombination by PCR. Genome Res,1994,4(3): 123130. 
［7］ Wurch T, Lestienne F,Pauwels P. A modified overlap extension PCR method to create chimeric genes in the absence of restriction enzymes. Biotechnology Techniques,1998, 12(9):653657. 
［8］ 李成华,房海燕,邓小云,等. 用改进的重叠区扩增基因拼接法构建中间缺失突变体. 中华医学遗传学杂志,2004,21(1):5255. Li C H ,Fang H Y,Deng X Y,et al.Chin J Med Genet, 2004,21(1):5255. 
［9］ Albrecht C, Baynes K, Sardini A,et al. Two novel missense mutations in ABCA1 result in altered trafficking and cause severe autosomal recessive HDL deficiency. Biochimica et Biophysica Acta,2004，1689(1):4757. 
［10］ Fitzgerald M, Mendez A, Moore K,et al. ATPbinding Cassette Transporter A1 contains an NH2terminal signal anchor sequence that translocates the protein’s first hydrophilic domain to the exoplasmic space. The Journal of Biological Chemistry,2001,276(18): 1513715145. 
［11］ Mukhamedova N,Fu Y,Bukrinsky M,et al. The role of different regions of ATPBinding Cassette Transporter A1 in cholesterol efflux. Biochemistry, 2007, 46(33):93889398. 
［12］ See R,CadayMalcolm R, Singaraja R,et al. Protein kinase A sitespecific phosphorylation regulates ATP binding Cassette A1 (ABCA1)mediated phospholipid efflux.J Biol Chem,2002, 277(44):4183541842. 
［13］ Faulkner L, Panagotopulos S, Johnson J,et al. An analysis of the role of a retroendocytosis pathway in ABCA1mediated cholesterol efflux from macrophages. Journal of Lipid Research,2008, 49(6): 13221332. 
［14］ Takahashi K, Kimura Y, Nagata K, et al. ABC proteins: key moleculaes for lipid homeostasis.Med Mol Morphol,2005,38(1):212. 
［15］ Rigot V,Hamon Y, Chambenoit O,et al. Distinct sites on ABCA1 control distinct steps required for cellular release of phospholipids. Journal of Lipid Research, 2002,43(12):20772086.