研究报告 |
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人PSF蛋白的原核表达及分析鉴定 |
王慧娟1, 兰洋1, 刘涛1, 李灵1,2 |
1. 四川大学生命科学院功能基因组实验室 成都 610064;
2. 海南医学院海南省热带病重点实验室 海口 571101 |
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Prokaryotic Expression, Analysis and Identification of Human Polypyrimidine Tract Binding Protein-associated Splicing Factor |
WANG Hui-juan1, LAN Yang1, LIU Tao1, LI Ling1,2 |
1. Functional Genome Laboratory, College of Life Science, Sichuan University, Chengdu 610064, China;
2. Hainan Provincial Key Laboratory of Tropical Medicine, Hainan Medical School, Haikou 571101, China |
引用本文:
王慧娟, 兰洋, 刘涛, 李灵. 人PSF蛋白的原核表达及分析鉴定[J]. 中国生物工程杂志, 2011, 31(06): 1-5.
WANG Hui-juan, LAN Yang, LIU Tao, LI Ling. Prokaryotic Expression, Analysis and Identification of Human Polypyrimidine Tract Binding Protein-associated Splicing Factor. China Biotechnology, 2011, 31(06): 1-5.
链接本文:
https://manu60.magtech.com.cn/biotech/CN/
或
https://manu60.magtech.com.cn/biotech/CN/Y2011/V31/I06/1
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[1] Sutherland L C, Rintala-Maki N D, White R D, et al. RNA binding motif (RBM) proteins: a novel family of apoptosis modulators? J Cellular Biochemistry, 2005, 94(1): 5-11.
[2] Peng R, Dye B T, Perez I, et al. PSF and p54 nrb bind a conserved stem in U5 snRNA. RNA, 2002, 8(6): 1334-1347.
[3] Mathur M, Tucker P W, Samuels H H. PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors. Mol Cell Biol, 2001, 21(10): 2298-2311.
[4] Bladen C L, Udayakumar D, Takeda Y, et al. Identification of the polypyrimidine tract binding protein-associated splicing factor p54(nrb) complex as a candidate DNA double-strand break rejoining factor, J Biol Chem, 2005, 280(10): 5205-5210.
[5] Akhmedov A T, Lopez B S. Human 100-kDa homologous DNA-pairing protein is the splicing factor PSF and promotes DNA strand invasion. Nucleic Acids Res, 2000, 28(11): 3022-3030.
[6] Zolotukhin A S, Michalowski D, Bear J, et al. PSF acts through the human immunodeficiency virus type1 mRNA instability elements to regulate virus expression. Mol Cell Biol, 2003, 23(7): 6618-6630.
[7] Song X, Wang B, Bromberg M E, et al. Retroviral-mediated transmission of a mouse VL30 RNA to human melanoma cells promotes metastasis in SCID mice. Proc Natl Acad Sci USA, 2002, 99 (9): 9269-6273.
[8] Song X, Sui A, Garen A. Binding of mouse VL30 retrotransposon RNA to PSF protein induces genes repressed by PSF: Effects on steroidogenesis and oncogenesis. Proc Natl Acad Sci USA, 2004, 101(2): 621-625.
[9] Song X, Sun Y, Garen A. Role of PSF protein and VL30 RNA in reversible gene regulation. Proc Natl Acad Sci USA, 2005, 102 (34): 12189-12193.
[10] Garen A, Song X. Regulatory roles of tumor-suppressor proteins and noncoding RNAs in cancer and normal cell function. Int J Cancer, 2008, 122(6): 1687-1691.
[11] Galietta A, Gunby R H, Redaelli S, et al. NPM/ALK binds and phosphorylates the RNA/DNA-binding protein PSF in anaplastic large-cell lymphoma. Blood, 2007, 110(7): 2600-2609. |
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