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中国生物工程杂志

CHINA BIOTECHNOLOGY
中国生物工程杂志  2013, Vol. 33 Issue (9): 119-125    
讲座     
移植细胞的种类及其有效性和安全性——细胞移植治疗连载之二
王佃亮
第二炮兵总医院药学部 北京 100088
The Types, Safety and Efficacity of the Transplanted Cells
WANG Dian-liang
Department of Pharmacy, The Second Artillery General Hospital, Beijing 100088, China
 全文: PDF(510 KB)   HTML
摘要: 用于移植治疗的细胞主要有肝细胞、胰岛细胞、树突状细胞、细胞因子诱导的杀伤细胞、淋巴因子激活的杀伤细胞、胚胎干细胞、造血干细胞、间充质干细胞等,每种细胞都有不同的生物学特性。在临床应用前,要严格按照国家食品药品监督管理局的有关规定,研究特定细胞制剂的生物学特性、药理学、毒理学等,进行动物和临床试验,确定适应症、禁忌症,评估有效性和安全性。正式获得国家食品药品监督管理局许可后,再进行相关临床研究和应用。
关键词: 细胞移植治疗体细胞干细胞    
Abstract: The cells used for cell transplantation therapy mainly consist of hepatocyte, islet cells, dendritic cells, cytokine-induced killer cells, lymphokine activated killer cells, embryonic stem cells, hemopoietic stem cells, and mesenchymal stem cells, etc. Every cell kind has different biological characteristics. Before clinic application, according to the related documents of State Food and Drug Administration, the specific cell agent is studied on its biological characteristics, pharmacology, and toxicology, etc. Animal experiments and clinical tests are carried on to assure its indications and contraindications for assessment of safety and efficacity. After a license has been obtained from State Food and Drug Administration, the related clinical researches and applications can be carried on.
Key words: Cell transplantation therapy    Somatic cell    Stem cell
收稿日期: 2013-07-08 出版日期: 2013-09-25
ZTFLH:  R617  
通讯作者: 王佃亮wangdianl@sina.com     E-mail: wangdianl@sina.com
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王佃亮. 移植细胞的种类及其有效性和安全性——细胞移植治疗连载之二[J]. 中国生物工程杂志, 2013, 33(9): 119-125.

WANG Dian-liang. The Types, Safety and Efficacity of the Transplanted Cells. China Biotechnology, 2013, 33(9): 119-125.

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https://manu60.magtech.com.cn/biotech/CN/        https://manu60.magtech.com.cn/biotech/CN/Y2013/V33/I9/119

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