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C-myc通过调控BubR1影响食管鳞癌细胞对紫杉醇的敏感性 |
胡敏, 宋培培, 湛晓琴, 吕自兰, 陈楚, 施琼, 翁亚光 |
重庆医科大学医学检验系 临床检验诊断学教育部重点实验室 重庆 400016 |
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C-Myc Affects Esophageal Squamous Cancer Sensitivity to Paclitaxel by Regulating BubR1 Expression |
HU Min, SONG Pei-pei, ZHAN Xiao-qin, LÜ Zi-lan, CHEN Chu, SHI Qiong, WENG Ya-guang |
The Key Laboratory of Laboratory Medical Diagnostics in Ministry of Education, Chongqing Medical University, Chongqing 400016, China |
引用本文:
胡敏, 宋培培, 湛晓琴, 吕自兰, 陈楚, 施琼, 翁亚光. C-myc通过调控BubR1影响食管鳞癌细胞对紫杉醇的敏感性[J]. 中国生物工程杂志, 2013, 33(4): 22-27.
HU Min, SONG Pei-pei, ZHAN Xiao-qin, LÜ Zi-lan, CHEN Chu, SHI Qiong, WENG Ya-guang. C-Myc Affects Esophageal Squamous Cancer Sensitivity to Paclitaxel by Regulating BubR1 Expression. China Biotechnology, 2013, 33(4): 22-27.
链接本文:
https://manu60.magtech.com.cn/biotech/CN/
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https://manu60.magtech.com.cn/biotech/CN/Y2013/V33/I4/22
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[1] Yusuf R Z, Duan Z, Lamendola D E, et al. Paclitaxel resistance: molecular mechanisms and pharmacologic manipulation. Curr Cancer Drug, 2003, 3(1): 1-19. [2] Menssen A, Epanchintsev A, Lodygin D, et al. C-MYC delays prometaphase by direct transactivation of MAD2 and BubR1: identification of mechanisms underlying c-MYC-induced DNA damage and chromosomal instability. Cell Cycle, 2007, 6(3): 339-352. [3] von Rahden, Stein H J, Puhringer-Oppermann F, et al. c-myc amplification is frequent in esophageal adenocarcinoma and correlated with the upregulation of VEGF-A expression. Neoplasia, 2006, 8(9): 702-707. [4] Fojo T, Menefee M. Mechanisms of multidrug resistance: the potential role of microtubule-stabilizing agents. Ann Oncol, 2007, 18 (5): 3-8. [5] Michael A Lampson, Tarun M Kapoor. The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments. Nat Cell Biol, 2004, 7(1): 93-98. [6] Fang G. Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex. Mol Biol Cell, 2002, 13(3): 755-766. [7] Dai W, Wang Q, Liu T, et al. Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency. Cancer Res, 2004, 64(2): 440-445. [8] Hanks S, Coleman K, Reid S, et al. Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B. Nat Genet, 2004, 36(11): 1159-1161. [9] Yamamoto Y, Matsuyama H, Chochi Y, et al. Overexpression of BUBR1 is associated with chromosomal instability in bladder cancer. Cancer Genet Cytogenet, 2007, 174(1): 42-47. [10] Tanaka K, Mohri Y, Ohi M, et al. Mitotic checkpoint genes, hsMAD2 and BubR1, in oesophageal squamous cancer cells and their association with 5-fluorouracil and cisplatin-based radiochemotherapy. Clin Oncol (R Coll Radiol), 2008, 20(8): 639-646. [11] Maia A F, Lopes C S, Sunkel C E. BubR1 and CENP-E have antagonistic effects upon the stability of microtubule-kinetochore attachments in Drosophila S2 cell mitosis. Cell Cycle, 2007, 6 (11): 1367-1378. [12] Shin H J, Baek K H, Jeon A H, et al. Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability. Cancer Cell, 2003, 4(6): 483-497. [13] Wang W, Xue L, Wang P. Prognostic value of beta-catenin, c-myc, and cyclin D1 expressions in patients with esophageal squamous cell carcinoma. Med Oncol, 2011, 28(1): 163-169. |
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