| 综述 |
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| 中心体周期相关蛋白磷酸化/去磷酸化及其功能的研究进展 |
| 谭锬1,3, 梁前进1,2 |
1. 北京师范大学生命科学学院 基因工程药物及生物技术北京市重点实验室 北京 100875;
2. 北京师范大学生命科学学院 细胞增殖及调控生物学教育部重点实验室 北京 100875;
3. 北京师范大学生命科学学院 抗性基因与分子发育北京市重点实验室 北京 100875 |
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| Research Progress on Centrosome Cycle Related Protein Phosphorylation/Dephosphorylation and the Involved Functions |
| TAN Tan1,3, LIANG Qian-jin1,2 |
1. College of Life Sciences, Beijing Normal University/Beijing Key Lab of Gene Engineering Drugs & Biological Technology, Beijing 100875, China;
2. College of Life Sciences, Beijing Normal University/Key Laboratory of Cell Proliferation and Regulation Biology of Ministry of Education, Beijing 100875, China;
3. College of Life Sciences, Beijing Normal University/Beijing Key Lab of Gene Resource and Molecular Development, Beijing 100875, China |
[1] Doxsey S. Re-evaluating centrosome function. Nature Reviews Molecular Cell Biology, 2001, 2(9): 688-698.
[2] Bornens M. Centrosome composition and microtubule anchoring mechanisms. Current Opinion in Cell Biology, 2002, 14(1): 25-34.
[3] Lüders J, Stearns T. Microtubule-organizing centres: a re-evaluation. Nature Reviews Molecular Cell Biology, 2007, 8(2): 161-167.
[4] Bettencourt-Dias M, Glover D M. Centrosome biogenesis and function: centrosomics brings new understanding. Nature Reviews Molecular Cell Biology, 2007, 8(6):451-463.
[5] Yamashita Y M, Mahowald A P, Perlin J R, et al. Asymmetric inheritance of mother versus daughter centrosome in stem cell division. Science, 2007, 315: 518-521.
[6] Gard D L, Hafezi S, Zhang T, et al. Centrosome duplication continues in cycloheximide-treated xenopus blastulae in the absence of a detectable cell cycle. Journal of Cell Biology, 1990, 110(6): 2033-2042.
[7] Barros T P, Kinoshita K, Hyman A A, et al. Aurora a activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules. Journal of Cell Biology, 2005, 170(7): 1039 -1046.
[8] Wei Y, Shen E Z, Zhao N, et al. Identification of a novel centrosomal protein CrpF46 involved in cell cycle progression and mitosis. Experimental Cell Research, 2008, 314: 1693-1707.
[9] Fukasawa K. Oncogenes and tumour suppressors take on centrosomes. Nature Reviews Cancer, 2007, 7(12): 911-924.
[10] Uetake Y, Sluder G. Cell cycle progression after cleavage failure: mammalian somatic cells do not possess a "tetraploidy checkpoint". Journal of Cell Biology, 2004, 165(5): 609-615.
[11] Meraldi P, Erich A N. Centrosome cohesion is regulated by a balance of kinase and phosphatase activities. Journal of Cell Biology, 2001, 114(20): 3749-3757.
[12] Lorca T, Bernis C, Vigneron S, et al. Constant regulation of both the MPF amplification loop and the Greatwall-PP2A pathway is required for metaphase II arrest and correct entry into the first embryonic cell cycle. Journal of Cell Biology, 2010, 123(13): 2281-2291.
[13] Kitagawa D, Fluckiger I, Polanowska J, et al. PP2A phosphatase acts upon SAS-5 to ensure centriole formation in C. elegans Embryos. Developmental Cell, 2011, 20(4): 550-562.
[14] Song M H, Liu Y, Anderson D E, et al. Protein phosphatase 2A-SUR-6/B55 regulates centriole duplication in C. elegans by controlling the levels of centriole assembly factors. Developmental Cell, 2011, 20(4): 563-571.
[15] Domingo-Sananes M R, Kapuy O, Hunt T, et al. Switches and latches: a biochemical tug-of-war between the kinases and phosphatases that control mitosis. Philosophical Transactions of the Royal Society B-biological Sciences, 2011, 366(1584): 3584-3594.
[16] Meraldi P, Nigg E A. The centrosome cycle. Febs Letters, 2002, 512(1-3):9-13.
[17] Tokuyama Y, Horn H F, Kawamura K, et al. Specific phosphorylation of nucleophosmin on Thr(199) by cyclin-dependent kinase 2-cyclin E and its role in centrosome duplication. Journal of Biological Chemistry, 2001, 276(24): 21529-21537.
[18] Ma Z, Kanai M, Kawamura K, et al. Interaction between ROCK II and nucleophosmin/B23 in the regulation of centrosome duplication. Molecular and Cellular Biology, 2006, 26(23): 9016-9034.
[19] Wang H F, Takenaka K, Nakanishi A, et al. BRCA2 and nucleophosmin coregulate centrosome amplification and form a complex with the Rho effector kinase ROCK2. Cancer Research, 2010, 71(1): 68-77.
[20] Chen Z H, Indjeian V B, McManus M, et al. CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells. Developmental Cell, 2002, 3(3): 339-350.
[21] D'Angiolella V, Donato V, Vijayakumar S, et al. SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation. Nature, 2010, 466(7302): 138-U161.
[22] Kasbek C, Yang C H, Yusof A M, et al. Preventing the degradation of Mps1 at centrosomes is sufficient to cause centrosome reduplication in human cells. Molecular Biology of the Cell, 2007, 18(11): 4457-4469.
[23] Mattison C P, Old W M, Steiner E, et al. Mps1 activation loop autophosphorylation enhances kinase activity. Journal of Biological Chemistry, 2007, 282(42): 30553-30561.
[24] Alvarado-Kristensson M, Rodriguez M J, Silio V, et al. SADB phosphorylation of γ-tubulin regulates centrosome duplication. Nature Cell Biology, 2009, 11(9): 1081-1086.
[25] Hergovich A, Kohler R S, Schmitz D, et al. The MST1 and hMOB1 tumor suppressors control human centrosome duplication by regulating NDR kinase phosphorylation. Current Biology, 2009, 19(20): 1692-1702.
[26] Cizmecioglu O, Warnke S, Arnold M, et al. Plk2 regulated centriole duplication is dependent on its localization to the centrioles and a functional polo-box domain. Cell Cycle, 2008, 7(22): 3548-3555.
[27] Chang J, Cizmecioglu O, Hoffmann I, et al. PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle. Embo Journal, 2010, 29(14): 2395-2406.
[28] Kitagawa D, Busso C, Fluckiger I, et al. Phosphorylation of SAS-6 by ZYG-1 is critical for centriole formation in C. elegans embryos. Developmental Cell, 2009, 17(6): 900-907.
[29] Bahtz R, Seidler J, Arnold M, et al. GCP6 is a substrate of Plk4 and required for centriole duplication. Journal of Cell Science, 2012, 125(2): 486-496.
[30] Verollet C, Colombie N, Daubon T, et al. Drosophila melanogaster γ-TuRC is dispensable for targeting γ-tubulin to the centrosome and microtubule nucleation. Journal of Cell Biology, 2006, 12(4):517-528.
[31] Haren L, Stearns T, Luders J. Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components. Plos One, 2009, 4(6):e5976.
[32] Zhang X Y, Chen Q, Feng J, et al. Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the γTuRC to the centrosome. Journal of Cell Science, 2009, 122 (13): 2240-2251.
[33] Lee K, Rhee K. PLK1 phosphorylation of pericentrin initiates centrosome maturation at the onset of mitosis. Journal of Cell Biology, 2011, 195(7): 1093-1101.
[34] Guarguaglini G, Duncan P I, Stierhof Y D, et al. The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles. Molecular Biology of the Cell, 2005, 16(3): 1095-1107.
[35] Hannak E, Kirkham M, Hyman A A, et al. Aurora-A kinase is required for centrosome maturation in caenorhabditis elegans. Journal of Cell Biology, 2001, 155(7): 1109-1115.
[36] Berdnik D, Knoblich J A. Drosophila aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis. Current Biology, 2002, 12(8):640-647.
[37] Maton G, Thibier C, Castro A, et al. Cdc2-cyclin B triggers H3 kinase activation of Aurora-A in Xenopus oocytes. Journal of Biological Chemistry, 2003, 278(24):21439-21449.
[38] Pascreau G, Delcros J G, Morin N, et al. Aurora-A kinase Ser349 phosphorylation is required during Xenopus laevis oocyte maturation. Developmental Biology, 2008, 317(2):523-530.
[39] Kinoshita K, Noetzel T L, Pelletier L, et al. Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis. Journal of Cell Biology, 2005, 170(7):1047-1055.
[40] Mori D, Yano Y, Toyo-Oka K, et al. NDEL1 phosphorylation by aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment. Molecular and Cellular Biology, 2007, 27(1):352-367.
[41] Wu C C, Yang T Y, Yu C T, et al. p53 negatively regulates Aurora A via both transcriptional and posttranslational regulation. Cell Cycle. 2012,11(18):3433-3442.
[42] Rosenblatt J, Cramer L P, Baum B, et al. Myosin II-dependent cortical movement is required for centrosome separation and positioning during mitotic spindle assembly. Cell, 2004, 117(3): 361-372.
[43] Cao J, Crest J, Fasulo B, et al. Cortical Actin dynamics facilitate early-stage centrosome separation. Current Biology, 2010, 20(8): 770-776.
[44] Wang W Q, Chen L Y, Ding Y B, et al. Centrosome separation driven by actin- microfilaments during mitosis is mediated by centrosome-associated tyrosine-phosphorylated cortactin. Journal of Cell Science, 2008, 121(8): 1334-1343.
[45] Tehrani S, Tomasevic N, Weed S, et al. Src phosphorylation of cortactin enhances actin assembly. Proceedings of the National Academy of Sciences of the United States of America, 2007, 104(29): 11933-11938.
[46] Tanenbaum M E, Macurek L, Galjart N, et al. Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly. Embo Journal, 2008, 27(24): 3235-3245.
[47] Smith E, Hegarat N, Vesely C, et al. Differential control of Eg5-dependent centrosome EMBO separation by Plk1 and Cdk1. Embo Journal, 2011, 30(11): 2233-2245.
[48] Mardin B R, Lange C, Baxter J E, et al. Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction. Nature Cell Biology, 2010, 12(12): 1166-U106.
[49] Busch C, Barton O, Morgenstern E, et al. The G(2)/M checkpoint phosphatase cdc25C is located within centrosomes. International Journal of Biochemistry & Cell Biology, 2007, 39(9): 1707-1713.
[50] Boutros R, Lorenzo C, Mondesert O, et al. CDC25B associates with a centrin 2-containing complex and is involved in maintaining centrosome integrity. Biology of the Cell, 2011, 103(2): 55-68.
[51] Shreeram S, Hee W K, Bulavin D V. Cdc25A serine 123 phosphorylation couples centrosome duplication with DNA replication and regulates tumorigenesis. Molecular and Cellular Biology, 2008, 28(24): 7442-7450.
[52] Boutros R, Ducommun B. Asymmetric localization of the CDC25B phosphatase to the mother centrosome during interphase. Cell Cycle, 2008, 7(3): 401-406.
[53] Martin-Granados C, Philp A, Oxenham S K, et al. Depletion of protein phosphatase 4 in human cells reveals essential roles in centrosome maturation, cell migration and the regulation of Rho GTPases. International Journal of Biochemistry & Cell Biology, 2008, 40(10): 2315-2332.
[54] Mardin B R, Agircan F G, Lange C, et al. Plk1 controls the Nek2A-PP1 gamma antagonism in centrosome disjunction. Current Biology, 2011, 21(13): 1145-1151.
[55] Eto M, Elliott E, Prickett T D, et al. Inhibitor-2 regulates protein phosphatase-1 complexed with NimA-related kinase to induce centrosome separation. Journal of Biological Chemistry, 2002, 277(46): 44013-44020.
[56] Leach C, Shenolikar S, Brautigan D L. Phosphorylation of phosphatase inhibitor-2 at centrosomes during mitosis. Journal of Biological Chemistry, 2003, 278(28): 26015-26020.
[57] Janssens V, Longin S, Goris J. PP2A holoenzyme assembly: in cauda venenum (the sting is in the tail). Trends in Biochemical Sciences, 2008, 33(3): 113-121.
[58] Mochida S, Ikeo S, Gannon J, et al. Regulated activity of PP2A-B55 delta is crucial for controlling entry into and exit from mitosis in Xenopus egg extracts. Embo Journal, 2009, 28(18): 2777-2785.
[59] Mochida S, Maslen S L, Skehel M, et al. Greatwall phosphorylates an inhibitor of protein phosphatase 2A that is essential for mitosis. Science, 2010, 330(6011): 1670-1673.
[60] Gharbi-Ayachi A, Labbe J C, Burgess A, et al. The substrate of greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A. Science, 2010, 330(6011): 1673-1677.
[61] Brownlee C W, Klebba J E, Buster D W, et al. The protein phosphatase 2A regulatory subunit twins stabilizes Plk4 to induce centriole amplification. Journal of Cell Biology, 2011, 195(2): 231-243.
[62] Voets E, Wolthuis R M F. MASTL is the human orthologue of greatwall kinase that facilitates mitotic entry, anaphase and cytokinesis. Cell Cycle, 2010, 9(17): 3591-3601.
[63] Boutros R, Lobjois V, Ducommun B. CDC25B involvement in the centrosome duplication cycle and in microtubule nucleation. Cancer Research, 2007, 67: 11557-11564.
[64] Sumiyoshi E, Sugimoto A, Yamamoto M. Protein phosphatase 4 is required for centrosome maturation in mitosis and sperm meiosis in C. elegans. Journal of Cell Science, 2002, 115 (7): 1403-1410.
[65] Lingle W L, Lutz W H, Ingle J N, et al. Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity. Proc Natl Acad Sci. USA, 1998, 95: 2950-2955.
[66] Weber R G, Bridger J M, Benner A, et al. Centrosome amplification as a possible mechanism for numerical chromosome aberrations in cerebral primitive neuroectodermal tumors with TP53 mutations. Cytogenet Cell Genet, 1998, 83:266-269.
[67] Sato N, Mizumoto K, Nakamura M, et al. Correlation between centrosome abnormalities and chromosomal instability in human pancreatic cancer cells. Cancer Genet Cytogenet, 2001, 126: 13-19.
[68] Pihan G A, Purohit A, Wallace J, et al. Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression. Cancer Res, 2001, 61: 2212-2219.
[69] Takayama K, Horie-Inoue K, Suzuki T, et al. TACC2 is an androgen-responsive cell cycle regulator promoting androgen-mediated and castration-resistant growth of prostate cancer. Mol Endocrinol, 2012, 26(5):748-761.
[70] Wang S, Li W, Liu N, et al. Nek2A contributes to tumorigenic growth and possibly functions as potential therapeutic target for human breast cancer. J Cell Biochem, 2012, 113(6): 1904-1914.
[71] Shen E Z, Lei Y, Liu Q, et al. Identification and characterization of INMAP, a novel interphase nucleus and mitotic apparatus protein that is involved in spindle formation and cell cycle progression. Exp Cell Res, 2009, 315: 1100-1116.
[72] Rangasamy V, Mishra R, Sondarva G, et al. Mixed-lineage kinase 3 phosphorylates prolyl-isomerase pinl to regulate its nuclear translocation and cellular function. Proc Natl Acad Sci USA, 2012, 109(21):8149-8154. |
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