酶催化聚合是合成环境友好高分子聚合物的有效方法之一。脂肪酶催化聚酯合成能在温和的条件下，高效率、高选择性地完成聚合反应，具有化学合成无可比拟的优越性。本文综述了脂肪酶催化简单的二酸或活性酯类与二醇缩聚、内酯开环聚合合成生物降解性聚酯，并简述了逐步生长聚合和内酯开环聚合的机制。最后，分析了脂肪酶催化合成聚酯的前景。

Enzyme catalyzed synthesis of polyesters is an eco-friendly and effective technique. By contrast with traditional chemical polymerization, lipase catalyzed reaction has the advantage of high efficiency, high selectivity, mildness. The review highlighted lipase catalyzed polycondensation reactions of simple diacids with diols and activated esters with diols, ring-opening polymerization of lactones leading to the formation of polyesters. The mechanisms of step-growth polymerization and ring-opening were briefly described. Finally, developmental perspective for biodegradable polyesters synthesised by lipase catalyzed was presented.