体外扩增造血干细胞是一个快速发展的领域，具有广泛的生物医学应用前景。由于传统的静态培养方法已经不适应大规模扩增造血干细胞的需要，因此许多类型的生物反应器被应用到造血细胞培养中来，出现了灌注式、搅拌式以及旋转式等类型的反应器。它们具有许多静态方法所不能比拟的优点，其培养效果也优于静态培养体系。
The ex vivo expansion of human hematopoietic stem cells (HSCs) is a rapidly developing area with a broad range of biomedical applications. Because the traditional static culture systems can hardly satisfy the ex vivo expansion of HSCs in a large scale, several kinds of bioreactors have been tested to culture these cells, such as perfusion chambers, stirred reactors and rotating reactors. The culture results with these bioreactors are usually much better than the static systems since the bioreactors have lots of advantages.
刘洋,刘天庆,范秀波,崔占峰,马学虎. 生物反应器在造血干细胞体外扩增中的应用[J]. 中国生物工程杂志, 2006, 26(0): 234-240.
. Application of bioreactors in the ex vivo expansion of hematopoietic stem cells. China Biotechnology, 2006, 26(0): 234-240.
https://manu60.magtech.com.cn/biotech/CN/ 或 https://manu60.magtech.com.cn/biotech/CN/Y2006/V26/I0/234
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