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PHP14沉默对肺癌细胞凋亡的影响及其机制 |
徐安健1, 李艳萌1, 李斯文1, 乌姗娜2, 张蓓1, 黄坚1 |
1. 首都医科大学附属北京友谊医院科研实验中心 北京 100875; 2. 首都医科大学附属北京友谊医院临床检验中心 北京 100875 |
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The Effect of PHP14 Knockdown on Lung Cancer Cells Apoptosis and Its Mechanism |
XU An-jian1, LI Yan-meng1, LI Si-wen1, WU Shan-na2, ZHANG Bei1, HUANG Jian1 |
1. Experimental Center, Beijing Friendship Hospital, Beijing 100875, China; 2. Clinical Laboratory Center, Beijing Friendship Hospital, Beijing 100875, China |
引用本文:
徐安健, 李艳萌, 李斯文, 乌姗娜, 张蓓, 黄坚. PHP14沉默对肺癌细胞凋亡的影响及其机制[J]. 中国生物工程杂志, 2017, 37(7): 12-17.
XU An-jian, LI Yan-meng, LI Si-wen, WU Shan-na, ZHANG Bei, HUANG Jian. The Effect of PHP14 Knockdown on Lung Cancer Cells Apoptosis and Its Mechanism. China Biotechnology, 2017, 37(7): 12-17.
链接本文:
https://manu60.magtech.com.cn/biotech/CN/10.13523/j.cb.20170705
或
https://manu60.magtech.com.cn/biotech/CN/Y2017/V37/I7/12
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[1] Pia E K, Pettersson G, Bo E K, et al. Identification and characterization of a mammalian 14-kDa phosphohistidine phosphatase. Eur J Biochem, 2002, 269(20):5016-5023. [2] Klumpp S, Hermesmeier J, Selke D, et al. Protein histidine phosphatase: a novel enzyme with potency for neuronal signaling. J Cereb Blood Flow Metab, 2002, 22(12):1420-1424. [3] Klumpp S, Bechmann G, Maurer A, et al. ATP-citrate lyase as a substrate of protein histidine phosphatase in vertebrates. Biochem Biophys Res Commun, 2003, 306(1):110-115. [4] Maurer A, Wieland T, Meissl F, et al. The b-subunit of G proteins is a substrate of proteinhistidine phosphatase. Biochem Biophys Res Commun, 2005, 334(4):1115-1120. [5] 徐安健, 蒋单懿, 黄凌云, 等. 人组氨酸磷酸酶PHP14的原核表达及其与Hsp90的体外互作研究. 中国生物工程杂志, 2010, 30(7): 7-11. Xu A J, Jiang S Y, Huang L Y, et al. Prokaryotic expression, purification of human 14-kDa phosphohistidine phosphatase and its interaction with HSP90in vitro. China Biotechnology, 2010, 30(7): 7-11. [6] Xu A J, Hao J, Zhang Z, et al. 14-kDa phosphohistidine phosphatase and its role in human lung cancer cell. Lung Cancer, 2010, 67(1): 48-56. [7] Xu A, Li X, Li S, et al. A novel role for 14-kDa phosphohistidine phosphatase in lamellipodia formation. Cell Adh Migr, 2016,7:1-8. [8] Xu A, Li X, Wu S, et al. Knockdown of 14-kDa phosphohistidine phosphatase expression suppresses lung cancer cell growth in vivo possibly through knockdownof NF-kappaB signaling pathway. Neoplasma, 2016,63(4):540-547. [9] Xu A J, Xia X H, Gu J C, et al. Clinical significance of PHPT1 in lung cancer. Chinese Medical Journal, 2010,123(22):3247-3251. [10] 徐安健, 崔永, 赵高潮, 等. 人组氨酸磷酸酶蛋白PHP14的过表达及其对NIH-3T3细胞体外增殖和非锚定依赖性生长的影响. 中国生物工程杂志, 2013, 33(6):7-11. Xu A J, Cui Y, Zhao G C, et al. The overexpression of PHP14 and its effect on NIH-3T3 cells proliferation in vitro and Anchor Independent Growth. China Biotechnology, 2013, 33(6):7-11. [11] Liu G, Pei F, Yang F, et al. Role of autophagy and apoptosis in non-small-cell lung cancer. Int J Mol Sci, 2017, 18(2): 367. [12] Vasilikos L, Spilgies L M, Knop J, et al. Regulating the balance between necroptosis, apoptosis and inflammation by inhibitors of apoptosis proteins. Immunol Cell Biol, 2017, 95:160-165. [13] Zheng J H, Viacava Follis A, Kriwacki R W, et al. Discoveries and controversies in Bcl-2 protein-mediated apoptosis. FEBS J. 2016, 83(14):2690-700. [14] Beesoo R, Neergheen-Bhujun V, Bhagooli R, et al. Apoptosis inducing lead compounds isolated from marine organisms of potential relevance in cancer treatment. Mutat Res, 2014, 768:84-97. |
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