[1] Kim Y,Kobayashi A,Sekido R,et al.Fgf9 and wnt4 act as antagonistic signals to regulate mammalian sex determination.PLoS Biol,2006,4(6):e187.
[2] Chen T M,Hsu C H,Shaw-Jenq Tsai,et al.AUF1 p42 isoform selectively controls both steady-state and PGE2-induc ed FGF9 mRNA decay. Nucleic Acids Research,2010,38(22):8061-8071.
[3] Mattei M G,Penault-Llorca F,Coulicr F,et al.The human FGF9 Gene maps to chromosomal region 13q11-q112. Genomics,1995,291(2):811-812.
[4] Colvin J S,Feldman B,Ornitz D M,et al.Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene.Developmental Dynamics,1999,216(1):72-88.
[5] Eriksson A E,Cousens L S,Weaver L H,et al.Three-dimensional structure of human basic fibroblast growth factor.PNAS,1991,88(8):3441-3445.
[6] Plotnikov A N,Eliseenkova A V,IbrahimiO A,et al.Structure of fibroblast growth factor9 reveals regions implicated in dimerization and autoinhibition.J Biol Chem,2001,276(6):4322-4329.
[7] Revest J M,De Moerlooze L,Dickson C.Fibroblast growth factor 9 secretion is mediated by a non-cleaved amino-terminal signal sequence.J Biol Chem,2000,275(11):8083-8090.
[8] Harmer N J,Robinson C J,Adam L E,et al.Multimers of the fibroblast grow the factor(FGF)FGF receptor saccharide complex are formed on long oligomers of heparin.Biochem J,2006,393(Pt3):741-748.
[9] Hung I H,Yu K,Lavine K J,et al.FGF9 regulates early hypertrophic chodrocyte differentiation and skeletal vascularizat-ion in the developing stylopod.Developmmental Biology,2007,307(12):300-313.
[10] Kettunen P,Thesleff I.Expression and function of FGFs-4,-8,and-9suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis.Dev Dyn,2004,211(3):256-268.
[11] Porntaveetus T,Otsuka-Tanaka Y,Albert Bason M,et al.Expression of fibroblast growth factors(FGFs) in murine tooth development.J Anat,2011,218(5):534-543.
[12] Nakagami M,Saito H,Matsuki N.Basic fibroblast growth factor and brain-derived neurotrophic factor promote survi-val and neuronal circuit formation in organotypic hippocampal culture.Jpn J Pharmacol,1997,75(4):319-326.
[13] Marini A M,Spiga G,Machetti I.Toward the development of strategies to prevent ischemic neuronal injury. in vitro studies.Ann NY Acad Sci,1997,825:209-219.
[14] Lin Y,Chen L,Lin C,et al.Neuron-derived FGF9 is essential for scaffold formation of bergmann radial fibers and migration of granule neurons in the cerebellum.Developmental Biology,2009,329(1):44-54.
[15] Kaye D M,Kelly R A,Smith T W.Cytokines and cardiac hypertrophy: roles of angiotensin II and basic fibroblast growth factor.Clin Exp Pharmacol Physiol,1996,3:S136-S141.
[16] Puk O,Moller G,Geerlof A,et al.The pathologic effect of a novel neomorphic Fgf9 Y162Callele is restricted to decreased vision and retarded lens growth.PLoS One,2011,6(8):23678.
[17] Gay D,Kwon O,Zhang Z K,et al.Fgf9 from dermal γδ T cells induces hair follicle neogenesis after wounding.Nat Med,2013,19(7):916-923.
[18] Al Alam D,Sala F G,Baptista S,et al.FGF9-Pitx2-FGF10 signaling controls cecal formation in mice . Developmental Biology,2012,369(2):340-348.
[19] Byron S A,Gartside M G,Wellens C L,et al.FGFR2 mutations are rare across histologic subtypes of ovarian cancer.Gynecol Oncol,2010,117(1):125-129.
[20] Dong X,Tang B,Li J,et al.Expression and purification of intact and functional soybean (Glycine max) seed ferritin complex in Escherichia coli.J Microbiol Biotechnol,2008,18(2):299-307.
[21] Nuc P, Nuc K.Recombinant protein production in Escherichia coli.Postepy Biochem,2006,52(4):448-456.
[22] 黄炜,余瑛,鲁秀敏,等.小鼠FGF9在大肠杆菌中的表达与纯化.西南农业学报,2009,22(6):1773-1775. Huang W,Yu Y,Lu X M,Fang J J,et al.Expression and purification of mouse fibroblast growth factor 9 in E.coli. Southwest China Journal of Agricultural Sciences,2009,22(6):1773-1775.
[23] 李慧,魏刚,于永利.以Bacmid-杆状病毒-昆虫细胞系统表达人FGF9.中国免疫学杂志,1999,15(10):440-443. Li H,Wei G,Yu Y L.Expression of human fibroblast growth factor 9 in bacmid-baculovirus expression system.Chinese Journal of Immunology,1999,15(10):440-443.
[24] 眭蕊,刘群,李锐锐,等.人FGF9慢病毒表达载体的构建、包装及鉴定.中国医药导报,2013,10(30):16-19. Sui R,Liu Q, Li R R,et al.Construction and identification of human FGF9 lentiviral expression vector.China Herald of Medicine,2013,10(30):16-19.
[25] Ohgino K,Soejima K,Yasuda H,et al.Expression of fibroblast growth factor 9 is associated with poorprognosis in patie- nts with resected non-small cell lung cancer.Lung Cancer,2014,83(1):90-96.
[26] 杨浩.miR-140-5p通过靶向调节TGFBRl和FGF9抑制肝细胞癌增殖和侵袭转移.长沙:中南大学,湘雅医院,2013. Yang H.MicroRNA-140-5 Psuppresses Tumor Growth and Metastasis by Targeting TGFBR1 and FGF9 in Hepatocellular carcinoma.Changsha:Central South University,Xiangya Hospital,2013.
[27] Li Z G,Mathew P,Yang J,et al.Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms.The Journal of Clinical Investigation,2008,118(8):2697-2710.
[28] Hendrix N D,Wu R,Kuick R,et al.Fibroblast growth factor has oncogenic activity and is a downstream target of Wnt signaling in ovarian endometrioid adenocarcinomas.Cancer Res,2006,66(3):1354-1362.
[29] Katoh M.Cancer genomics and genetics of FGFR2(review).Int J Oncol,2008,33(2):233-237.
[30] Steele I A,Edmondson R J,Leung H Y,et al.Ligands to FGF receptor2-Ⅲb induce proliferation,motility protection from cell death and cytoskeletal rearrangements in epithelial ovarian cancer cell lines.Growth Factors,2006,24(1): 45-53.
[31] Wing L,Chen H,Chuang P,et al.The mammalian target of rapamycin P70 ribosomal S6 kinase but not phesphatidylinositi3 kinaseakt signaling is responsible for fibroblast growth factor-9-induced cell proliferation.J Biol Chem,2005,280(20):19937-19947.
[32] Schreiber N B,Spicer L J.Effects of fibroblast growth factor 9(FGF9)on steroidogenesis and gene expression and control of FGF9 mRNA in bovine granulosa cells.Endocrinology,2012,153(9):4491-4501.
[33] Kathpalia V P,Mussak E N,Chow S S,et al.Genome-wide transcripttional profiling in human squamous cell carcinoma of the skin identifies unique tumor-associated signatures.J Dermatol,2006,33(5):309-318.
[34] Mulder D J,Pacheco I,Hurlbut D J,et al.FGF9 induced proliferative response to eosinophilic inflammation in oesophagitis.Gut,2009,58(2):166-173.
[35] Wang C K,Chang H,Chen P H,et al.Aryl hydrocarbon receptor activation and overexpression upregulated fibroblast growth factor-9 in human lung adenocarcinomas.Int J Cancer,2009,125(4):807-815.
[36] Schwartz D R,Wu R,Kardia S L R,et al.Novel candidate targets of β-catenin/T-cell factor signaling identified by gene expression profiling of ovarian endometrioid adeno Carcinomas.Cancer Research,2003,63(11):2913-2922.
[37] Kard K,Gross J L,Crickard U,et al.Basic Fibroblast growth factor and receptor expression in human ovarian cancer.Gynecol Oncol,1994,55(2):277-284.
[38] Sarkar F H,Li Y,Wang Z,et al.The role of nutraceuticals in the regulation of Wnt and Hedgehog signaling in cancer.Cancer Metastasis Rev,2010,29(3):383-394.
[39] Valverde-Franco G,Liu H,Davidson D,et al.Defective bone mineralization and osteopenia in young adult FGFR3-/-mice.Hum Mol Genet,2004,13(3):271-284.
[40] Ignelzi M A Jr,Wang W,Young A T.Fibroblast growth factors lead to increased Msx2 expression and fusion in calvarial sutures.J Bone Miner Res,2003,18(4):751-759.
[41] Dai J W,Wang J,Lu J T,et al.The effect of co-culturing costal chondrocytes and dental pulp stem cells combined with exogenous FGF9 protein on chondrogenesis and ossification in engineered cartilage. Biomaterials,2012,33(31):7699-7711.
[42] Taiwo Y O.Approaches in developing new anabolic therapies.International Conference on Osteoporosis and Bone Research,Beijing,2003.Beijing:Chinese Society of Osteoporosis and Bone MineralResearch Chinese Medical Association.International Chinese Hard Tissue Society,2003:10-11.
[43] Wang S X,Bendele A M,Moore E M.The chondroprotective effect of FGF9 in an experiment model of osteoarthritis.Osteoarthritis and Cartilage,2012,20(1):S40-S41.
[44] Ornizt D M.FGF signaling in the developing endochondral skeleton.Cytokine & Growth Factor Reviews, 2005,16(2):205-213.
[45] Weksler N B,Lunstrum G P,Reid E S,et al.Differential effects of fibroblast growth factor(FGF)9 and FGF2 on proliferation,differentiation and terminal differentiation of chondrocytic cells in vitro.Biochem J,1999,342(Pt3):677-682.
[46] Aikawa T,Segre G V,Lee K.Fibroblast growth factor inhibits chondrocytic growth through induction of p21 and subsequent inactivation of cyclin E-Cdk2.J Biol Chem,2001,276(31):29374-29352
[47] Xiao L P,Naganawa T,Obugunde E,et al.Stat1 controls postnatal bone formation by regulating fibroblast growth factor signaling in osteoblasts.J Biol Chem,2004,279(26): 27743-27752.
[48] Minina E,Kreschel C,Naski M C,et al.Interaction of FGF,IHH/Pthlh,and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation.Dev Cell,2002,3(3):439-449.
[49] Wu X L,Gu M M,Yang J M,et al.A unique point mutation in the fibroblast growth factor 9 gene(FGF9) defines a new Multiple Synostosis Syndrome in a large Chinese family. Am J Hum Genet,2008.
[50] Wu X L,Gu M M,Huang L,et al.Multiple synostoses syndrome Is due to a missense mutation in exon 2 of FGF9 gene.The American Journal of Human Genetics,2009,85(1):53-63.
[51] Cory A T,Boyer A,Silversides D W,et al.Presumptive pre-Sertoli cells express genes involved in cell proliferation and cell signaling during a critical window in early testis differentiation.Mol Reprod Dev,2007,74(12):1491-1504.
[52] Chen T M,Kuo P L.Microsatellite in the 3'untranslated region of human fibroblast growth factor9(FGF9) gene exhibits pleiotropic effect on modulating FGF9 protein expression.Hum Mutat,2007,28(1):98.
[53] DiNapoli L,Capel B.SRY and the standoff in sex determination.Mol Endocrinol,2008,22(1):1-9.
[54] Schmahl J,Capel B.Cell proliferation is necessary for the determination of male fate in the gonad.Dev Biol,2003,258(2):264-276.
[55] Colvin J S,Green R P,Schmahl J,et al.Male-to-female sex reversal in mice lacking fibroblast growth factor 9.Cell,2001,104(6):875-889.
[56] Gassei K,Schlatt S.Testicular morphogenesis:comparison of in vivo and in vitro models to study male gonadal development.Ann N Y Acad Sci,2007,1120:152-167.
[57] Merchant-Larios H,Moreno-Mendoza N,Buehr M.The role of the mesonephros in cell differentiation and morphogenesis of the mouse fetal testis.Int J Dev Biol,1993,37(3):407-415.
[58] Cool J,Carmona F D,Szucsik J C,et al.Peritubular myoid cells are not the migrating population required for testis cord formation in the XY gonad.Sex Dev,2008,2(3):128-133.
[59] Loke J,Pearlman A,Radi O,et al.Mutations in MAP3K1 tilt the balance from SOX9/FGF9 to WNT/β-catenin signaling.Human Molecular Genetics,2014,3(4):1073-1083.
[60] Kim Y,Capel B. Balancing the bipotential gonad between alternative organ fates: A new perspective on an old problem.Developmental Dynamics,2006,235:2292-2300.
[61] Jameson S A,Lin Y T,Capel B.Testis development requires the repression of Wnt4 by Fgf signaling. Developmental Biology,2012,370(1):24-32.
[62] Bagher-i F S,Sim H,Harley V R,et al.Loss of Fgfr2 leads to partial XY sex reversal.Biol,2008,314(1):71-83.
[63] Maatouk D M,DiNapoli L,Capel B,et al.Stabilization of bcatenin in XY gonads causes male-to-female sex-reversal.Human Molecular Genetics,2008,17(19):2949-2955.
[64] Bowles J,Feng C W,Spiller C,et al.FGF9 suppresses meiosis and promotes male germ cell fate in mice. Developmental Cell,2010,19(3):440-449.
[65] Machado A Z,da Silva T E,Frade Costa E M,et al.Absence of inactivating mutations and deletions in the DMRT1 and FGF9 genes in a large cohort of 46,XY patients with gonadal dysgenesis.European Journal of Medical Genetics,2012,55(12):690-694.
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