综述 |
|
|
|
|
基于CRISPR/Cas系统的单碱基编辑技术研究进展* |
王玥,牟彦双(),刘忠华 |
东北农业大学黑龙江省动物细胞与遗传工程重点实验室 哈尔滨 150030 |
|
Progress of CRISPR/Cas Base Editing System |
WANG Yue,MU Yan-shuang(),LIU Zhong-hua |
Heilongjiang Key Laboratory of Animal Cell and Genetic Engineering, Northeast Agricultural University, Harbin 150030, China |
[1] |
Jansen R, Gaastra1 W, Embden V, et al. Identification of genes that are associated with DNA repeats in prokaryotes. Mol Microbiol, 2002,43(6):1565-1575.
pmid: 11952905
|
[2] |
Jinek M, Chylinski K, Fonfara I, et al. A Programmable dual-RNA-guided DNA endo nuclease in adaptive bacterial immunity. Science, 2012,337(6096):816-821.
pmid: 22745249
|
[3] |
Cong L, Ran A, Cox D, et al. Multiplex genome engineering using CRISPR/Cas systems. Science, 2013,339(6121):819-823.
pmid: 23287718
|
[4] |
Ran F A, Wright J, Zhang F, et al. Genome engineering using the CRISPR-Cas9 system. Nat Protoc, 2013,8(11):2281-2308.
pmid: 24157548
|
[5] |
Komor A C, Zuris J A, Liu D R, et al. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage. Nature, 2016,533(7603):420-424.
pmid: 27096365
|
[6] |
Gaudelli N M, Komor A C, Rees H A, et al. Programmable base editing of A*T to G*C in genomic DNA without DNA cleavage. Nature, 2017,551(7681):464-471.
pmid: 29160308
|
[7] |
Grunewald J, Zhou R H, Lareau G A, et al. A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing. Nat Bio, 2020,38(7):861-864.
|
[8] |
Zhang X H, Zhu B Y, Chen L, et al. Dual base editor catalyzes both cytosine and adenine base conversions in human cells. Nat Bio, 2020,38(7):856-860.
|
[9] |
Abudayyeh O O, Gootenberg J S, Franklin B, et al. A cytosine deaminase for programmable single-base RNA editing. Science, 2019,365(6451):382-386.
pmid: 31296651
|
[10] |
Jin S, Zong Y, Gao Q, et al. Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice. Science, 2019,364(6437):292-295.
doi: 10.1126/science.aaw7166
pmid: 30819931
|
[11] |
Zuo E, Sun Y D, Wei W, et al. Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos. Science, 2019,364(6437):289-292.
pmid: 30819928
|
[12] |
Tarantino M E, Dow B J, Drohat A C, et al. Nucleosomes and the three glycosylases: high, medium, and low levels of excision by the uracil DNA glycosylase superfamily. DNA Repair, 2018,72(6):56-63.
|
[13] |
Mali P, Yang L H, Esvelt K M, et al. RNA-guided human genome engineering via Cas9. Science, 2013,339(6121):823-826.
|
[14] |
Kunkel T A, Erie D A. Eukaryotic mismatch repair in relation to DNA replication. Annu Rev Genet, 2015,49(5):291-313.
|
[15] |
Komor A C, Zhao K T, Packer M S, et al. Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity. Sci Adv, 2017, 3(8): eaao4774.
pmid: 28845449
|
[16] |
Carter R J, Parsons J L. Base excision repair: a pathway regulated by post-translational modifications. Mol Cell Biol, 2016,36(10):1426-1437.
doi: 10.1128/MCB.00030-16
pmid: 26976642
|
[17] |
Jiang W, Feng S J, Huang S S, et al. BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity. Cell Res, 2018,28(8):855-861.
pmid: 29875396
|
[18] |
Nishida K, Arazoe T, Yachie N, et al. Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems. Science, 2016, 353(6305): aaf8729.
pmid: 27634516
|
[19] |
Ma Y, Zhang J Y, Yin W J, et al. Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells. Nat Methods, 2016,13(12):1029-1035.
pmid: 27723754
|
[20] |
Hess G T, Fresard L, Han K, et al. Directed evolution using dcas9-targeted somatic hypermutation in mammalian cells. Nature Methods, 2016,13(12):1036-1042.
doi: 10.1038/nmeth.4038
pmid: 27798611
|
[21] |
Kim Y B, Komor A C, Levy J M, et al. Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions. Nat Biotechnol, 2017,35(4):371-376.
pmid: 28191901
|
[22] |
Li X, Wang Y, Liu Y J, et al. Base editing with a Cpf1-cytidine deaminase fusion. Nat Biotechnol, 2018,36(4):324-327.
doi: 10.1038/nbt.4102
pmid: 29553573
|
[23] |
Wang L, Wang Y, Liu Y J, et al. Enhanced base editing by co-expression of free uracil DNA glycosylase inhibitor. Cell Res, 2017,27(10):1289-1292.
doi: 10.1038/cr.2017.111
pmid: 28849781
|
[24] |
Zuo E, Sun Y D, Yuan T L, et al. A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects. Nat Methods, 2020,17(6):1-5.
|
[25] |
Zhang X H, Chen L, Zhu B Y, et al. Increasing the efficiency and targeting range of cytidine base editors through fusion of a single-stranded DNA-binding protein domain. Nat Cell Biol, 2020,22(6):1-11.
|
[26] |
Hu J H, Miller S M, Geurts M H, et al. Evolved Cas9 variants with broad PAM compatibility and high DNA specificity. Nature, 2018,556(7699):57-63.
doi: 10.1038/nature26155
pmid: 29512652
|
[27] |
Hua K, Tao X, Zhu J K. Expanding the base editing scope in rice by using Cas9 variants. Plant Biotechnol J, 2019,17(2):499-504.
doi: 10.1111/pbi.12993
pmid: 30051586
|
[28] |
Yang L, Zhang X H, Wang L R, et al. Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants. Protein Cell, 2018,9(9):814-819.
pmid: 30066232
|
[29] |
Hua K, Tao X P, Yuan F T, et al. Precise A.T to G.C Base Editing in the Rice Genome. Mol Plant, 2018,11(4):627-630.
doi: 10.1016/j.molp.2018.02.007
pmid: 29476916
|
[30] |
Koblan L W, Doman J L, Wilson C, et al. Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction. Nat Biotechnol, 2018,36(9):843-846.
doi: 10.1038/nbt.4172
pmid: 29813047
|
[31] |
Daub H, Specht K, Ullrich A. Strategies to overcome resistance to targeted protein kinase inhibitors. Nat Rev Drug Discov, 2004,3(12):1001-1010.
doi: 10.1038/nrd1579
pmid: 15573099
|
[32] |
Yeh W H, Oleinik S O, Levy J M, et al. In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness. Sci Transl Med, 2020, 12(546): eaay9101.
doi: 10.1126/scitranslmed.abd0088
pmid: 32493789
|
[33] |
Tang X, Sretenovic S, Ren Q R, et al. Plant prime editors enable precise gene editing in rice cells. Mol Plant, 2020,13(5):667-670.
doi: 10.1016/j.molp.2020.03.010
pmid: 32222487
|
[34] |
Zong Y, Wang Y P, Li C, et al. Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion. Nat Biotechnol, 2017,35(5):438-440.
pmid: 28244994
|
[35] |
Kim K, Ryu S M, Kim S T, et al. Highly efficient RNA-guided base editing in mouse embryos. Nat Biotechnol, 2017,35(5):435-437.
pmid: 28244995
|
[36] |
Liang P, Sun W, Sun Y, et al. Effective gene editing by high-fidelity base editor 2 in mouse zygotes. Protein & Cell, 2017.
doi: 10.1007/s13238-020-00764-0
pmid: 33141416
|
[37] |
Xie J K, Li N, Liu Q S, et al. Efficient base editing for multiple genes and loci in pigs using base editors. Nature Communications, 2019,10(1):2852-2865.
pmid: 31253764
|
[38] |
Yang J, Li J Y, Suzuki K C, et al. Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding. Cell Res, 2017,27(9):1178-1181.
doi: 10.1038/cr.2017.86
pmid: 28685772
|
[39] |
Wang L R, Li L X, Ma Y, et al. Reactivation of γ-globin expression through Cas9 or base editor to treat β-hemoglobinopathies. Cell Research, 2020,30(3):276-278.
doi: 10.1038/s41422-019-0267-z
pmid: 31911671
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
|
Shared |
|
|
|
|
|
Discussed |
|
|
|
|