研究报告 |
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研究miR-219下调TGFBR2影响ENDMT途径抑制急性心肌梗死 |
郭义威(),王松涛,崔卫刚 |
新乡医学院人体解剖学教研室 新乡 453003 |
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Inhibition of Acute Myocardial Infarction by miR-219 on ENDMT Pathway by Targeting TGFBR2 |
Yi-wei GUO(),Song-tao WANG,Wei-gang CUI |
Department of Anatomy, Xinxiang Medical University, Xinxiang 453003, China |
[1] |
田国芳, 宋玉勤, 程宇彤 , 等. 急性心肌梗死介入治疗术后的康复运动疗法研究进展. 心脏杂志, 2016,28(4):492-495.
|
|
Tian G F, Song Y Q, Cheng Y X , et al. Progress in rehabilitation exercise therapy after interventional therapy for acute myocardial infarction. J Cardiol, 2016,28(4):492-495.
|
[2] |
Toltl L J, Swystun L L , Pepler L , et a1. Protective effects of activated protein C in sepsis. Thromb Haemost, 2008,100(4):582-592.
doi: 10.1160/TH08-03-0159
pmid: 18841279
|
[3] |
Travers J G, Kamal F A , Bobbins J , et a1. Cardiac fihrosis: the fibroblast awakens. Circ Res, 2016,118(6):1021-1040.
doi: 10.1161/CIRCRESAHA.115.306565
|
[4] |
林昌建, 孔辉, 解卫平 , 等. EndMT在血管重塑中的作用及相关信号通路. 江苏医药, 2016,42(12):1384-1386.
|
|
Lin C J, Kong H, Xie W P , et al. The role of EndMT in vascular remodeling and related signaling pathways. Jiangsu Medical Journal, 2016,42(12):1384-1386.
|
[5] |
Fidler I J . Seed and soil revisited: contribution of the organ microenvironment to cancer metastasis. Surg Oncol Clin N Am, 2001,10(2):257-269.
doi: 10.1016/S1055-3207(18)30064-4
|
[6] |
张召才, 严静, 虞意华 , 等. 心肌炎小鼠心肌纤维化与心脏上皮/内皮间充质转化的关系. 中国病理生理杂志, 2011,27(9):1692-1696.
doi: 10.3969/j.issn.1000-4718.2011.09.006
|
|
Zhang Z C , Yan J, Qi Y H , et al. Relationship between myocardial fibrosis and cardiac epithelial/endothelial mesenchymal transition in myocarditis mice. Chinese Journal of Pathophysiology, 2011,27(9):1692-1696.
doi: 10.3969/j.issn.1000-4718.2011.09.006
|
[7] |
Zeisberg E M, Tarnavski O, Zeisberg M , et al. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat Med, 2007,13(8):952-961.
|
[8] |
Davis U E, Senger D R . Endothelial extracellular matrix: biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization. Circ Res, 2005,97(11):1093-1107.
doi: 10.1161/01.RES.0000191547.64391.e3
|
[9] |
Yang M, Zhu M, Tang L , et al. Polymorphisms of TGF-β1 and TGFBR2 in relation to coronary artery disease in a Chinese population. Clin Biochem, 2016,49(12):873-878.
doi: 10.1016/j.clinbiochem.2016.05.022
pmid: 27234600
|
[10] |
Liu Z, Yang D, Xie P , et al. MiR-106b and miR-15b modulate apoptosis and angiogenesis in myocardial infarction. Cell Physiol Biochem, 2012,29(5-6):851-862.
doi: 10.1159/000258197
|
[11] |
Liu X, Zhang Y, Du W , et al. MiR-223-3p as a novel microRNA regulator of expression of voltage-gated K+ channel Kv4.2 in acute myocardial infarction. Cell Physiol Biochem, 2016,39(1):102-114.
doi: 10.1159/000445609
|
[12] |
Medici D, Potenta S, Kalluri R . Transforming growth factot-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signaling. Biochem, 2011,437(3):515-520.
doi: 10.1042/BJ20101500
|
[13] |
Olivieri F, Antonicelli R, Lorenzi M , et al. Diagnostic potential of circulating miR-499-5p in elderly patients with acute non ST-elevation myocardial infarction. Int J Cardiol, 2013,167(2):531-536.
doi: 10.1016/j.ijcard.2012.01.075
pmid: 22330002
|
[14] |
Lv P, Zhou M, He J , et al. Circulating miR-208b and miR-34a are associated with left ventricular remodeling after acute myocardial infarction. Int J Mol Sci, 2014,15(4):5774-5788.
doi: 10.3390/ijms15045774
|
[15] |
Rui Z, Chao L, Hui P , et al. Expression of circulating miR-486 and miR-150 in patients with acute myocardial infarction. BMC Cardiovasc Disord, 2015,15(1):1-7.
doi: 10.1186/1471-2261-15-1
pmid: 25592444
|
[16] |
Xian L, Zhanwei F, Tianshu Z , et al. Plasma miR-1, miR-208, miR-499 as potential predictive biomarkers for acute myocardial infarction: An independent study of Han population. Exp Gerontol, 2015,72:230-238.
doi: 10.1016/j.exger.2015.10.011
pmid: 26526403
|
[17] |
Cheng H Y, Papp J W, Varlamova O , et al. microRNA modulation of circadian-clock period and entrainment. Neuron, 2007,54(5):813-829.
doi: 10.1016/j.neuron.2007.05.017
|
[18] |
Lukiw W J . Micro-RNA speciation in fetal, adult and Alzheimer’s disease hippocampus. Neuroreport, 2007,18(3):297-300.
doi: 10.1097/WNR.0b013e3280148e8b
pmid: 17314675
|
[19] |
Shi W, Du J, Qi Y , et al. Aberrant expression of serum miRNAs in schizophrenia. J Psychiatr Res, 2012,46(2):198-204.
doi: 10.1016/j.jpsychires.2011.09.010
|
[20] |
周依蒙, 郑鹏翔, 戴晓勇 , 等. 微小RNA-678调控心肌梗死相关转录因子FoxP1的表达研究. 国际心血管病杂志, 2018,45(1):4 4-47.
|
|
Zhou Y M, Zheng P X, Dai X Y , et al. MicroRNA-678 regulates the expression of FoxP1, a transcription factor related to myocardial infarction. International Journal of Cardiovascular Diseases, 2018,45(1):44-47.
|
[21] |
Ha J S, Kim Y H . A sporadic case of Loeys-Dietz syndrome type I with two novel mutations of the TGFBR2 gene. Korean Journal of Pediatrics, 2011,54(6):272-275.
doi: 10.3345/kjp.2011.54.6.272
pmid: 21949523
|
[22] |
Jamsheer A, Henggeler C, Wierzba J , et al. A new sporadic case of early-onset Loeys-Dietz syndrome due to the recurrent mutation p.R528C in the TGFBR2 gene substantiates interind Ⅳidual clinical variability. Journal of Applied Genetics, 2009,50(4):405-410.
doi: 10.1007/BF03195701
pmid: 19875893
|
[23] |
刘艳华, 李宾公 . 内皮间质转分化在心血管疾病中的研究进展. 医学研究生学报, 2016,29(8):872-876.
doi: 10.16571/j.cnki.1008-8199.2016.08.020
|
|
Liu Y H, Li B G . Advances in the study of endothelial mesenchymal transition in cardiovascular diseases. Journal of Medical Postgraduate, 2016,29(8):872-876.
doi: 10.16571/j.cnki.1008-8199.2016.08.020
|
[24] |
马坤岭, 刘晶, 倪杰 , 等. 微炎症致脂质稳态失调在小鼠心肌纤维化中的作用. 中华心血管病杂志, 2013,41(7):602-606.
doi: 10.3760/cma.j.issn.0253-3758.2013.07.019
|
|
Ma K L, Liu J, Ni J , et al. The role of microinflammation-induced lipid homeostasis in myocardial fibrosis in mice. Chinese Journal of Cardiovascular Diseases, 2013,41(7):602-606.
doi: 10.3760/cma.j.issn.0253-3758.2013.07.019
|
[25] |
鞠延玲, 朱国伟, 赵旭 , 等. miR-330-5p负性调控ADAM17基因抑制人心脏微血管内皮细胞的间质转化. 贵州医药, 2016,40(10):1011-1014.
|
|
Yan Y L, Zhu G W, Zhao X , et al. Negative regulation of ADAM17 gene by miR-330-5p inhibits mesenchymal transition of human cardiac microvascular endothelial cells. Guizhou Medicine, 2016,40(10):1011-1014.
|
[26] |
史可欣, 梅焕平 . 转化生长因子-β调控内皮间充质转化的研究进展. 山西医药杂志, 2017,46(5):522-526.
doi: 10.3969/j.issn.0253-9926.2017.05.009
|
|
Shi K X, Mei H P . Research progress of transforming growth factor-β in regulating endothelial mesenchymal transition. Shanxi Medical Journal, 2017,46(5):522-526.
doi: 10.3969/j.issn.0253-9926.2017.05.009
|
[27] |
Liu Z, Zhang K, Wang Q L , et al. Serum TGF-β1 in patients with acute myocardial infarction. Br J Biomed Sci, 2016,73(2):90-93.
doi: 10.1080/09674845.2016.1166683
pmid: 27181170
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