| ［1］ Ketchum R E B,Croteau R B. Recent progress toward an understanding of taxol biosynthesis in plant cell cultures. In: Ageta H, Aimi N, Ebizuka Y, et al. Towards nature medicine research in the 21st century, the International Symposium on Natural Medicines. Kyoto, Japan, 1997. Japan: Elsevier Science B V, 1998, 339~348
［2］ Rowinsky E K, Cazenave L A, and Donebower R C. Taxol: a novel investigational antimicrotubule agent. J Nat Cancer Inst, 1990, 82(15):1247~1259
［3］ Holmes F A, Walters R S, Theriault R L, et al. Phase II trial of Taxol, an active drug in the treatment of metastatic breast cancer. J Natl Cancer Inst, 1991, 83(24):1797~1805
［4］ Wani M C, Taylor H L, Wall M E, et al. The isolation and structure of Taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. J Am Chem Soc, 1971, 93(9):2325~2327
［5］ Ronald L, Hanson S, John M, et al. Sitespecific enzymatic hydrolysis of taxanes at C-10 and C-13 J Biol Chem, 1994, 269(35):22145~22149
［6］ 骆建新, 陈永勤, 刘占杰．紫杉醇生物合成相关酶基因的克隆与表达．中国生物工程杂志, 2003, 23(6):35~40
Luo J X, Chen Y Q, Liu Z J. China Biotechnology, 2003, 23(6):35~40
［7］ 黄新, 黄璐琦, 邱德有．紫杉醇生物合成途径中相关酶的研究进展．中国生物工程杂志, 2002, 22(5):27~33
Huang X, Huang L Q, Qiu D Y. China Biotechnology, 2002, 22(5):27~33
［8］ Vongpaseuth K, Roberts S C. Advancements in the understanding of paclitaxel metabolism in tissue culture. Curr Pharm Biotechnol, 2007, 8(4):219~236
［9］ 朱平，王伟，程克棣．药用植物功能基因．中国生物工程杂志, 2001, 24(2):3~8
Zhu P, Wang W, Cheng K D. China Biotechnology, 2001, 24 (2):3~8
［10］ Jennewein S, Rithner C D, Williams R M, et al. Taxoid metabolism: taxoid 14βhydroxylase is a cytochrome P450dependent monooxygenase. Arch Biochem Biophys, 2003, 413(2): 262~270
［11］ 胡新玲，徐妙云，刘德虎，等．紫杉烷14β一羟基化酶基因片段的克隆及其植物表达载体的构建．分子植物育种，2006，4(2)：243~250
Hu X L, Xu M Y, Liu D H, et al. Molecular Plant Breeding，2006，4(2)：243~250
［12］ Kim C H, Kim K I, Chung I S. Expression of modified green fluorescent protein in suspension culture of Taxus cuspidata. J Micro Biotech, 2000, 10(1):91~94
［13］ Ketchum R E B, Croteau R B. Stable transformation and longterm maintenance of transgenic Taxus cell suspension cultures. Plant Cell Rep, 2007, 26(7):1025~1033
［14］ 胡雅琴, 肖娅萍, 王孝安, 等．几种松科植物基因组总DNA的提取．西北植物学报, 2004, 24(3):523~526
Hu Y Q, Xiao Y P, Wang X A, et al. Acta Bot Borea1Occident Sin, 2004, 24(3):523~526
［15］ Ho C K, Chang S H, Lung J H, et al. The strategies to increase Taxol production by using Taxus mairei cells transformed with TS and DBAT genes. International Journal of Applied Science and Engineering, 2005, 3(3):179~185
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