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Advances in Programmed Cell Death in Staphylococcus aureus Infection |
WU Zhi-hang1,2,3,PAN Hai-bang1,**(),RONG Yao1,TANG Ming-zheng1,CUI Yan1,2,3,WANG Tian-ming1,2,3 |
1 The First College of Clinical Medicine, Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China 2 Gansu Provincial Engineering Laboratory for the Creation of New Traditional Chinese Medicine Products,Lanzhou 730000, China 3 Gansu Provincial Key Laboratory of Chinese Medicine Formulas Excavation and Innovative Transformation,Lanzhou 730000, China |
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Abstract Programmed cell death (PCD) is a collective term for the intrinsically regulated death of cells. Different forms of cell death are caused by their own programmed regulation during the growth and development of organisms and stress responses to the environment and diseases. PCD includes apoptosis, pyroptosis, necroptosis, autophagy and ferroptosis. It is not only essential for the growth and development of organisms, but also plays an important role in intervening in the process of pathogens invasion. Staphylococcus aureus can regulate various forms of PCD such as apoptosis, pyroptosis, necroptosis and autophagy in host cells, thereby affecting bacterial infection. This article reviews the crosstalk between Staphylococcus aureus infection and PCD to further understand the relationship between Staphylococcus aureus and cell death, in order to provide new ideas for the diagnosis and treatment of clinical Staphylococcus aureus infection.
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Received: 04 April 2023
Published: 01 December 2023
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Corresponding Authors:
**Hai-bang PAN
E-mail: phbwbb@126.com
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