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Research Progress on the Biogenesis and Function of piRNAs |
YAN Yu-jia,ZOU Ling() |
State Key Laboratory of Oral Diseases,National Clinical Research Center for Oral Diseases, Department of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China |
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Abstract PiRNA is a member of non-coding small RNA, which is commonly detected in germline cells. Previously scholars used to believe that piRNA mainly plays a role in maintaining the function of stem cells,formation of the gametes and silencing foreign transposon genes.But recent discoveries which show the piRNA traces in somatic cells have led to greater interest in its biogenesis and further function. The discovery, structure, function and gene regulation of piRNA were reviewed.
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Received: 07 January 2021
Published: 01 June 2021
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Corresponding Authors:
Ling ZOU
E-mail: zouling@scu.edu.cn
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