Orginal Article |
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Functions of RNA Editing Factors and Its Mechanisms in Plant Organelles |
WANG Ke-ru,ZHU Hong-liang() |
College of Food Science and Nutrutuinal Engineering, China Agricultural University, Beijing 100083, China |
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Abstract In flowering plants, cytosine C at hundreds of sites is usually converted into uracil U by deamination in mitochondrials and chloroplasts, which is a regulation mechanism of genetic information at the transcriptional level. RNA editing requires protein-protein or protein-RNA interaction to assemble into a complex"editosome" for recognition at special sites in plant organelles. Reachers have found that plant RNA editing is regulated by editosome pentapeptide repeat PPR proteins, and nor-PPR protein including that RNA editing factor interacting proteins/multiple organellar RNA editing factor (RIP/MORF), organelle RNA recognition motif(ORRM) proteins, organelle zinc-finger (OZ) proteins and others. These explain that plant RNA editing not only has a high diversity in PPR specific factors, but also nor-PPR protein components. The absence of RNA editing will cause adverse effects such as stunted growth, development of plants and fruit ripening. The most recent progress in the field and discuss the editosomes for the evolution of RNA editing and for futue findings were systematically summarized.
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Received: 15 July 2019
Published: 18 April 2020
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Corresponding Authors:
Hong-liang ZHU
E-mail: hlzhu@cau.edu.cn
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