| Orginal Article |
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| The Expression and Clinical Significance of CD177 + Neutrophils in Patients with Ulcerative Colitis |
ZHANG Yan-ting,GUO Yu-feng,YANG Zhi-hong,YANG Shao-qi( ) |
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Abstract Objective: To analyze the clinical significance of CD177 + neutrophils in ulcerative colitis (UC) by comparing the expression differences of CD177 + neutrophils in peripheral blood of UC patients with normal controls. Methods: Peripheral blood of 30 UC patients and 20 normal controls were collected, and the expression of neutrophils CD177 + was detected by flow cytometry, and compare the expression difference of CD177 in the two groups. Results: The expression of CD177 + neutrophils in peripheral blood of UC patients was significantly higher than the normal control group (P<0.01), the expression of CD177 + neutrophils in peripheral blood of UC patients was significantly higher than that of the mild UC patients (P<0.05), and the count of CD177 + neutrophils in peripheral blood of UC patients was correlated with Mayo score (r=0.384,P=0.036). Conclusion: The expression of CD177 + neutrophils in UC patients was significantly increased and closely related to the activity of the disease, which may reflect the clinical activity of UC.
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Received: 30 August 2019
Published: 20 September 2019
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Corresponding Authors:
Zhi-hong YANG,Shao-qi YANG
E-mail: shaoqiynh@163.com
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