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Research Progress on Xylose Transporters of Saccharomyces cerevisiae |
Jun HUANG1,2(),Ren-zhi WU1,2,Qi LU1,2,Zhi-long LU1,2 |
1 National Engineering Research Center for Non-Food Biorefinery, Nanning 530007, China 2 State Key Laboratory of Non-Food Biomass and Enzyme Technology, Nanning 530007, China |
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Abstract Technologies for the production of biothanol are receiving increased attention around the world owing to concerns over the global warming. Lignocellulosic biomass is a great potential resource for the production of biofuels because it is largely abundant, inexpensive and renewable organic material. Significant efforts, many of which have been successful, have been made to convert these lignocellulosic biomass to valuable products, such as biofuels. Sustainable development in lignocellulosic bioethanol production has major challenge due to high cost of production. There are several issues such as efficient utilization of pentose sugars present in lignocelluloses, economical production of lignocellulolytic enzymes with high specificity, cost-effective pre-treatment of lignocellulosic biomass, etc. Genetically modified yeast strains have been approached to utilize pentose and hexose sugars for bioethanol production. However, these strains showed limited xylose consumption. Saccharomyces cerevisiae rely on the capacity of endogenous hexose transporters for xylose uptake, since S. cerevisiae lacks a xylose-specific transport system. Hence, there are several strategies that have been applied to engineer the yeasts which could improve the xylose transportation. latest advancements in S. cerevisiae xylose transporter genes were discussed.
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Received: 01 August 2017
Published: 21 March 2018
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