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中国生物工程杂志

China Biotechnology
China Biotechnology  2013, Vol. 33 Issue (9): 79-84    DOI:
    
Protein Acetylation in Prokaryotes
BI Jing, ZHANG Xue-lian
School of Life Sciences, Fudan University, Shanghai 200433, China
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Abstract  In addition to histones, recent evidences suggest many non-histone proteins are subject to lysine acetylation. Furthermore, lysine acetylation status has been shown to influence several fundamental cellular pathways, including cellular differentiation and metabolism. Protein lysine acetylation and its regulatory enzymes have thus emerged as a frontier for research in mammalian cells. Recent studies support that protein acetylation occurs prevalently in prokaryotes and broadly impacts prokaryotes physiology. An emerging theme from these studies is that metabolic enzymes involved in central metabolic pathways and intermediary metabolisms are subjected to acetylation. To explore more rapidly the impact of protein acetylation in bacteria, we will summarize the current examples of protein acetylation in prokaryotes, discuss the emerging link between acetylation and central metabolism and understand the importance of protein acetylation in bacteria.

Key wordsAcetylation      Lysine      Prokaryote     
Received: 25 February 2013      Published: 25 September 2013
ZTFLH:  Q51  
Cite this article:

BI Jing, ZHANG Xue-lian. Protein Acetylation in Prokaryotes. China Biotechnology, 2013, 33(9): 79-84.

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https://manu60.magtech.com.cn/biotech/     OR     https://manu60.magtech.com.cn/biotech/Y2013/V33/I9/79

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