|
|
|
| Development Present Situation,Problems and Solve Method of Somatic Cell Nuclear Transfer |
| LÜ xin1,2, DU Wei-hua1, ZHU Hua-bin1 |
1. Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100094, China;
2. College of Animal Science & Technology, Gansu Agrcultural Unversity, Lanzhou 730070, China |
|
|
|
Abstract Somatic cell nuclear transfer (SCNT)is widely used in animal hunsbandry.However, the low efficiency restricted its application severely. Almost all the cloned animals have the hypertrophic placenta and aberrantly epigenetic inheritance which also result into the low efficiency of the cloning technology. The current progresses of SCNT were summarized and a new method, tetraploid compensation, to improve the placenta hypertrophy and the efficiency cloning by epigenetic modification were disccussed.
|
|
Received: 11 October 2012
Published: 25 April 2013
|
|
|
|
|
[1] 裴雪涛, 干细胞实验指南. 2006, 北京: 科学出版社.Pei X T, Guidelines of Stem Cell Experiments.Beijing: Science Press.2006.
[2] Wilmut I, Schnieke A E, McWhir J, et al. Viable offspring derived from fetal and adult mammalian cells. Nature, 1997, 385(6619): 810-813.
[3] Wakayama T, Perry A C, Zuccotti M, et al. Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature, 1998,394(6691): 369-374.
[4] Baguisi A, Behboodi E, Melican D T, et al. Production of goats by somatic cell nuclear transfer. Nat Biotechnol, 1999,17(5): 456-461.
[5] Kato Y, Tani T, Tsunoda Y. Cloning of calves from various somatic cell types of male and female adult, newborn and fetal cows. Journal of Reproduction and Fertility, 2000,120(2): 231-237.
[6] Polejaeva I A, Chen S H, Vaught T D, et al. Cloned pigs produced by nuclear transfer from adult somatic cells. Nature, 2000,407(6800): 86-90.
[7] Kitiyanant Y, Saikhun J, Chaisalee B, et al. Somatic cell cloning in Buffalo (Bubalus bubalis): effects of interspecies cytoplasmic recipients and activation procedures. Cloning Stem Cells, 2001,3(3): 97-104.
[8] Chesne P, Adenot P G, Viglietta C, et al. Cloned rabbits produced by nuclear transfer from adult somatic cells. Nat Biotechnol, 2002,20(4): 366-369.
[9] Zhou Q, Le R J, Friec G, et al. Generation of fertile cloned rats by regulating oocyteactivation. Science, 2003,302: 1179.
[10] Galli C, Lagutina I, Crotti G, et al. Pregnancy: a cloned horse born to its dam twin. Nature, 2003,424(6949): 635.
[11] Lee B C, Kim M K, Jang G, et al. Dogs cloned from adult somatic cells. Nature, 2005,436(7051): 641.
[12] Li Z, Sun X, Chen J, et al. Cloned ferrets produced by somatic cell nuclear transfer. Dev Biol, 2006,293(2): 439-448.
[13] You J, Lee J, Hyun S H, et al. L-carnitine treatment during oocyte maturation improves in vitro development of cloned pig embryos by influencing intracellular glutathione synthesis and embryonic gene expression. Theriogenology, 2012,78(2): 235-243.
[14] Xu W B, Wang Y S, Li Y Y, et al. Valproic acid improves the in vitro development competence of bovine somatic cell nuclear transfer embryos. Cellular Reprogramming, 2012,14(2): 138-145.
[15] You J, Kim J, Lee H, et al. MG132 treatment during oocyte maturation improves embryonic development after somatic cell nuclear transfer and alters oocyte and embryo transcript abundance in pigs. Molecular Reproduction and Development, 2012,79(1): 41-50.
[16] Inoue K, Ogonuki N, Mochida K, et al. Effects of donor cell type and genotype on the efficiency of mouse somatic cell cloning. Biol Reprod, 2003,69(4): 1394-1400.
[17] Ganier O, Bocquet S, Peiffer I, et al. Synergic reprogramming of mammalian cells by combined exposure to mitotic Xenopus egg extracts and transcription factors. Proc Natl Acad Sci U S A, 2011,108(42): 17331-17336.
[18] Xiong X R, Wang L J, Wang Y S, et al. Different preferences of IVF and SCNT bovine embryos for culture media. Cambridge University Press 2012 dio:10.1017/S0967199412000184[1]Zygote, 2012,1-9.
[19] Parn P, Plaas M, Nomm M, et al. Effects of culture conditions and gene transfection on the development of bovine somatic cell nuclear transfer embryos. Reprod Fertil Dev, 2012,25(1): 172.
[20] Wang L J, Zhang H, Wang Y S, et al. Scriptaid improves in vitro development and nuclear reprogramming of somatic cell nuclear transfer bovine embryos. Cell Reprogram, 2011,13(5): 431-439.
[21] Ogura A, Inoue K, Wakayama T. Recent advancements in cloning by somatic cell nuclear transfer. Philos Trans R Soc Lond B Biol Sci, 2013,368(1609): 20110329.
[22] Kishigami S, Wakayama S, Hosoi Y, et al. Somatic cell nuclear transfer: infinite reproduction of a unique diploid genome. Exp Cell Res, 2008,314(9): 1945-1950.
[23] Loi P, Clinton M, Vackova I, et al. Placental abnormalities associated with post-natal mortality in sheep somatic cell clones. Theriogenology, 2006,65(6): 1110-1121.
[24] 张家新,孟昭霞,张向丽,等. 影响克隆牛生产效率之因素研究.畜牧兽医科学, 2007,23(12): 5-9.Zhang J X, Meng Z X, Zhang X L. Study on factors affecting the production of cloned bovine. Chinese Agricultural Science Bulletin, 2007,23(12): 5-9.
[25] Watanabe S, Nagai T. Survival of embryos and calves derived from somatic cell nuclear transfer in cattle: a nationwide survey in Japan. Anim Sci J, 2011,82(2): 360-365.
[26] Wakisaka-Saito N, Kohda T, Inoue K, et al. Chorioallantoic placenta defects in cloned mice. Biochem Biophys Res Commun, 2006,349(1): 106-114.
[27] Wakayama T, Rodriguez I, Perry A C, et al. Mice cloned from embryonic stem cells. Proc Natl Acad Sci U S A, 1999,96(26): 14984-14989.
[28] Rideout W M, Eggan K, Jaenisch R. Nuclear cloning and epigenetic reprogramming of the genome. Science, 2001,293(5532): 1093-1098.
[29] Rideout W M, K. Eggan, Jaenisch R. Nuclear cloning and epigenetic reprogramming of the genome. Science, 2001,293(5532): 1093-1098.
[30] Wakisaka N, Inoue K, Ogonuki N, et al. Ultrastructure of placental hyperplasia in mice: comparison of placental phenotypes with three different etiologies. Placenta, 2008,29(8): 753-759.
[31] Hill J R, Burghardt R C, Jones K, et al. Evidence for placental abnormality as the major cause of mortality in first-trimester somatic cell cloned bovine fetuses. Biology of Reproduction, 2000,63(6): 1787-1794.
[32] 杨荣荣,李相运. DNA 甲基化与克隆动物的发育异常. 遗传, 2007,29(9): 1043-1048.Yang R R, Li X Y. DNA methylation and development abnormalities in cloned animals. Hereditas, 2007,29(9):1043-1048.
[33] Goyal R, Yellon S M, Longo L D, et al. Placental gene expression in a rat 'model’ of placental insufficiency. Placenta, 2010,31: 568-575.
[34] Guillomot M, Taghouti G, Constant F, et al. Abnormal expression of the imprinted gene Phlda2 in cloned bovine placenta. Placenta, 2010,31(6): 482-490.
[35] Chavatte-Palmer P, Camous S, Jammes H, et al. Placental perturbations induce the developmental abnormalities often observed in bovine somatic cell nuclear transfer. Placenta, 2011, 1(6): 1-6.
[36] Hoffert-Goeres K A, Batchelder C A, Bertolini M, et al. Angiogenesis in day-30 bovine pregnancies derived from nuclear transfer. Cloning Stem Cells, 2007,9(4): 595-607.
[37] Lee R S, Peterson A J, Donnison M J, et al. Cloned cattle fetuses with the same nuclear genetics are more variable than contemporary half-siblings resulting from artificial insemination and exhibit fetal and placental growth deregulation even in the first trimester. Biology of Reproduction, 2004,70(1): 1-11.
[38] Palmieri C, Loi P, Reynolds L P, et al. Placental abnormalities in ovine somatic cell clones at term: A light and electron microscopic investigation. Placenta, 2007,28(5-6): 577-584.
[39] Tanaka S, Oda M, Toyoshima Y, et al. Placentomegaly in cloned mouse concepti caused by expansion of the spongiotrophoblast layer. Biol Reprod, 2001,65(6): 1813-1821.
[40] El-Hashash A H, Warburton D, Kimber S J. Genes and signals regulating murine trophoblast cell development. Mech Dev, 2010,127(1-2): 1-20.
[41] Oda M, Shiota K, Tanaka S. Trophoblast cell lineage in cloned mouse embryos. Development Growth & Differentiation, 2010,52(3): 285-291.
[42] Jouneau A, Zhou Q, Camus A, et al. Developmental abnormalities of NT mouse embryos appear early after implantation. Development, 2006,133(8): 1597-1607.
[43] Lin J, Shi L, Zhang M, et al. Defects in trophoblast cell lineage account for the impaired in vivo development of cloned embryos generated by somatic nuclear transfer. Cell Stem Cell, 2011,8(4): 371-375.
[44] Talbot N C, Powell A M, Caperna T J, et al. Proteomic analysis of the major cellular proteins of bovine trophectoderm cell lines derived from IVP, parthenogenetic and nuclear transfer embryos: Reduced expression of annexins I and II in nuclear transfer-derived cell lines. Anim Reprod Sci, 2010,120(1-4): 187-202.
[45] Rici R E, Facciotti P R, Ambrosio C E, et al. Cell cycle and apoptosis in normal and cloned bovine near-term placentae. Anim Reprod Sci, 2009,115(1-4): 29-38.
[46] Kawasumi M, Anzai M, Takehara T. Abnormal distrbution of chromosomes in the frist division of nuclear transferred mouse embryos. Journal of Reproduction and Development, 2007,53(3): 615-622.
[47] Mizutani E, Yamagata K, Ono T, et al. Abnormal chromosome segregation at early cleavage is a major cause of the full-term developmental failure of mouse clones. Developmental Biology, 2012,364(1): 56-65.
[48] Wang Yingying, Hai Tang, Liu Zichuan, et al. HSPC117 deficiency in cloned embryos causes placental abnormality and fetal death. Biochemical and Biophysical Research Communications, 2010,397: 407-412.
[49] Bourc’his D, Le Bourhis D, Patin D, et al. Delayed and incomplete reprogramming of chromosome methylation patterns in bovine cloned embryos. Curr Biol, 2001,11(19): 1542-1546.
[50] Su J. Oxamflatin significantly improves nuclear reprogramming, blastocyst quality, and in vitro development of bovine SCNT embryos. PLoS ONE, 2011,6(8): 1-14.
[51] Chung Y G, Ratnam S, Chaillet J R, et al. Abnormal regulation of DNA methyltransferase expression in cloned mouse embryos. Biol Reprod, 2003,69(1): 146-153.
[52] Miki H, Wakisaka N, Inoue K, et al., Embryonic rather than extraembryonic tissues have more impact on the development of placental hyperplasia in cloned mice. Placenta, 2009,30(6): 543-546.
[53] 李相运,周荣艳. 利用四倍体补偿技术制备ES小鼠的技术方法. 解剖动物学, 2006,37(6): 724-727.Li X Y, Zhou R Y. Technique of producing mice derived from embryonic stem cells by tetraploid embryo complementation. Acta Anatomica Sinica, 2006,37(6):724-727.
[54] Eggan K, Akutsu H, Loring J, et al. Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation. Proc Natl Acad Sci U S A, 2001,98(11): 6209-6214.
[55] Tang S, Wang Y, Zhang D, et al. Reprogramming donor cells with oocyte extracts improves in vitro development of nuclear transfer embryos. Anim Reprod Sci, 2009,115(1-4): 1-9.
[56] Wossidlo M, Nakamura T, Lepikhov K, et al. 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming. Nature Communications, 2011,2:241.
[57] Lan J, Song Y L, Hua S, et al. cDNA cloning of goat DNA methyltransferase 1, screening of shRNA vectors and influences to development of nuclear transfer embryos. Agricultural Sciences in China, 2010,9(7): 1035-1040. |
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
| |
Shared |
|
|
|
|
| |
Discussed |
|
|
|
|
