Advances in methodology for aptamer selection

China Biotechnology

2008, Vol. 28

Issue (1): 113-118 DOI:

Advances in methodology for aptamer selection

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Abstract

The methods for aptamer selection have been modified and developed in recent years. Selection efficiency has been increased due to the improvement in separation of bound and unbound nucleic acids; applicability of aptamers has been improved due to the development of primer-free SELEX and the utilization of short oligonucleotide library; more research requirements have been satisfied due to the functional modifications of aptamer selection methods. All the methodological advances enhance the potential value of aptamers in basic researches and clinical applications.

Key words： Apatmer SELEX Methodology

Received: 30 August 2007 Published: 25 January 2008

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. Advances in methodology for aptamer selection. China Biotechnology, 2008, 28(1): 113-118.

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https://manu60.magtech.com.cn/biotech/ OR https://manu60.magtech.com.cn/biotech/Y2008/V28/I1/113

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