中国生物工程杂志

Object: To study the proliferation of hCTGF on cells and its biological function on bone injury healing. Methods: The fibroblast with potential differentiation transfected by eukaryotic gene delivery system was transferred into the experiment animal with bone fracture. The data were attained by molecular biology and clinical orthopedic technique detection analysis. Results: The results demonstrated an obvious proliferation of hCTGF on cells, suggesting that hCTGF have the biological activity of repairing bone injury via gene therapy approach. The observation provides a new activity factor and new treatment approach for bone injury in clinics.