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Cyclodextrin and its derivatives as non-viral gene vectors |
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Abstract Cyclodextrin (CD) is gradually applied in the nonviral gene vector system, due to its biocompatibility and flexibility of tailing via structural modification, polymerization or supramolecular combination. This paper reviews the ideas and research progress of the CD, its low molecular derivatives, CD polymers and CD supramolecular combination in the field of norviral gene vectros, and discuss their "structure - safety - transfection efficiency" relationships.
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Received: 09 April 2008
Published: 25 October 2008
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