Progress in the Regulative Mechanism of Specific MiRNA

China Biotechnology

2008, Vol. 28

Issue (2): 106-109 DOI:

Progress in the Regulative Mechanism of Specific MiRNA

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Abstract

MicroRNAs (miRNAs) are a newly identified class of non-protein-coding small RNAs that play important roles in multiple biological processes. Recent evidence indicates that the expression of many miRNAs is both temporally and spatially regulated by RNA editing, differential processing and tissue-specific enhancers, and the potential for ultimately designing molecular medicines based on the modulation of miRNAs seems good. A better understanding of the mechanism which regulates miRNAs is very helpful to reveal the pathogenesis of some diseases, discover novel molecular targets for treatment by interference, and even develope an effective gene therapy. Therefore, the latest progress in the mechanism regulating miRNAs is summarized in the paper.

Key words： miRNA specificity regulative mechanism

Received: 25 September 2007 Published: 25 February 2008

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Cite this article:

. Progress in the Regulative Mechanism of Specific MiRNA. China Biotechnology, 2008, 28(2): 106-109.

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https://manu60.magtech.com.cn/biotech/ OR https://manu60.magtech.com.cn/biotech/Y2008/V28/I2/106

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