Research Progress in the Fermentative Production of Exopolysaccharides by <em>Klebsiella</em> sp

China Biotechnology

2010, Vol. 30

Issue (12): 123-127 DOI:

Research Progress in the Fermentative Production of Exopolysaccharides by Klebsiella sp

DOU Chang, DU Jun, JI Xiao-jun, Nie Zhi-kui, GAO Zhen, HUANG He

State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing 210009, China

Download:

HTML

PDF(417KB) HTML
Export: BibTeX | EndNote (RIS)

Abstract

The progress in the production of exopolysaccharides by Klebsiella sp. is discussed, including composition, function and fermentation process of the exopolysaccharides. And the problems in the process of exopolysaccharides production are also discussed. It is pointed out that the research emphasis should be placed on using the mathematic tools to optimize the fermentation process and modifying downstream recovery process. Then the comparison with their counterparts and exoploitation of the potential function of the exopolysaccharides will be focused on.

Key words： Klebsiella sp. Exopolysaccharides Fermentation Progress

Received: 24 August 2010 Published: 25 December 2010

ZTFLH:

Q819

	Service
	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	DOU Chang
	DU Jun
	JI Xiao-jun
	Nie Zhi-kui
	GAO Zhen
	HUANG He

Cite this article:

DOU Chang, DU Jun, JI Xiao-jun, Nie Zhi-kui, GAO Zhen, HUANG He. Research Progress in the Fermentative Production of Exopolysaccharides by Klebsiella sp. China Biotechnology, 2010, 30(12): 123-127.

URL:

https://manu60.magtech.com.cn/biotech/ OR https://manu60.magtech.com.cn/biotech/Y2010/V30/I12/123


[1]	Sugihara R, Oiso Y, Matsumoto Y, et al. Production of an immunosuppressive polysaccharide, AZ9,in the culture of Klebsiella oxytoca strain TNM3. Journal of Bioscience and Bioengineering, 2001, 92(5): 485-487.

[2]	刘红英, 薛长湖, 张辉, 等. 产酸克雷伯氏菌胞外多糖单糖组成的气相色谱分析. 中国食品学报, 2006, 6(2): 113-116.

	Liu H Y, Xue C H, Zhang H, et al. Journal of Chinese Institute of Food Science and Technology, 2006, 6(2): 113-116.

[3]	Bryan B A, Linhardt R J, Daniels L. Variation in composition and yield of exopolysaccharides produced by Klebsiella sp. strain K32 and Acinetobacter calcoaceticus BD4. Appl Environ Microbiol, 1986, 51(6): 1304-1308.

[4]	林永成, 周世宁. 海洋微生物及其代谢产物. 北京: 化学工业出版社, 2001. 364-365.

	Lin Y C, Zhou S N. Marine Microorganisms and Their Metabolites. Beijing: Chemical Industry Press, 2001. 364-365.

[5]	Feng L, Li X F, Du G C, et al. Characterization and fouling properties of exopolysaccharide produced by Klebsiella oxytoca. Bioresource Technology, 2009, 100:3387-3394.

[6]	Corsaro M M, Castro D C, Naldi T, et al. 1H and 13C NMR characterization and secondary structure of the K2 polysaccharide of Klebsiella pneumoniae strain 52145. Carbohydrate Research, 2005, 340: 2212-2217.

[7]	Mitra A, Nath R K, Biswas S, et al. A comparative study on the physicochemical properties of bacterial capsular polysaccharides from different serotypes of Klebsiella. Journal of Photochemistry and Photobiology, 2006, 178: 98-105.

[8]	张燕, 李轻舟, 陈锦英. 肺炎克雷伯氏菌荚膜多糖的免疫活性研究. 工业微生物, 2005, 20: 18-20.

	Zhang Y, Li Q Z, Chen J Y. Industrial Microbiology, 2005, 20: 18-20.

[9]	张沫. 高效微生物絮凝菌的筛选及其特性研究. 哈尔滨:哈尔滨工业大学,2006.

	Zhang M. Separation of Bioflocculation Bacteria and Study on Its Characteristics. Harbin: Harbin Institute of Technology, 2006.

[10]	罗平, 罗固源. 克雷伯氏杆菌产生的絮凝剂处理垃圾渗滤液的研究. 中国材料科技与设备, 2006, 2: 60-63.

	Luo P, Luo G Y. Chinese Materials Science Technology & Equipment, 2006, 2: 60-63.

[11]	Santos V L, Guimaraes W V, Barros E G, et al. Fermentation of maltose and starch by Klebsiella oxytoca P2. Biotechnology Letters, 1998, 20(12): 1179-1182.

[12]	刘志鸿, 牟海津. 克雷伯氏菌胞外多糖的制备与组成分析. 海洋水产研究, 2008, 29(1): 8-11.

	Liu Z H, Mou H J. Marine Fishers Research. 2008, 29(1):8-11.

[13]	刘红英, 薛长湖, 王琦, 等. Klebsiella oxytoca XCH-1菌产胞外粗多糖发酵. 无锡轻工大学大学学报, 2004, 23(5): 16-21.

	Liu H Y, Xue C H, Wang Q, et al, Journal of Wuxi University of Light Industry, 2004, 23(5): 16-21.

[14]	张燕, 李轻舟, 杜连祥,等. 肺炎克雷伯氏菌荚膜多糖表达量评价指标的建立及发酵条件优化. 工业微生物, 2006, 32(2): 16-32.

	Zhang Y, Li Q Z, Du L X, et al. Industrial Microbiology, 2006, 32(2): 16-32.

[15]	Ochuba G U, von Riesen V L. Fermentation of polysaccharides by Klebsielleae and other facultative bacilli. Appl Environ Microbiol. 1980, 39: 988-992.

[16]	Dlamini A M, Peiris P S. Biopolymer production by a Klebsiella oxytoca isolate using whey as fermentation substrate. Biotechnology Letters, 1997, 19: 127-130.

[17]	Baldi F, Minacci A, Pepi M, et al. Gel sequestration of heavy metals by Klebsiella oxytoca isolated from iron mat. FEMS Microbiology Ecology, 2001, 36: 169-174.

[18]	Kao C M, Lin C C, Liu J K, et al. Biodegradation of the metal-cyano complex tetracyanonickelate(II) by Klebsiella oxytoca. Enzyme and Microbial Technology, 2004, 35: 405-410.

[19]	Chen C Y, Kao C M, Chen S C, et al. Biodegradation of tetracyanonickelate by Klebsiella oxytoca under anaerobic conditions. Desalination, 2009, 249:1212-1216.

[20]	Peiris P S, Dlamini A M, Bavor H J, et al. Optimization of bioprocess conditions for exopolysaccharide production by Klebsiella oxytoca. World Journal of Microbiology & Biotechnology, 1998, 14: 917-919.

[21]	Ramírez-Castillo M L, Uribelarrea J L. Improved process for exopolysaccharide production by Klebsiella pneumoniae sp. pneumoniae by a fed-batch strategy. Biotechnology Letters, 2004, 26: 1301-1306.

[22]	刘成梅游海. 天然产物有效成分的分离与应用. 北京: 化学工业出版社, 2003, 302-304.

	Liu C M, You H. Natural Products Isolation and Application. Beijing: Chemical Industry Press, 2003, 302-304.

[23]	李树品, 蒋千里, 楚杰,等. 产酸克雷伯氏菌的分离及其特性的研究. 山东科学, 1991, 4(3): 9-25.

	Li S P, Jiang Q L, Chu J, et al. Shandong Science, 1991, 4(3): 9-25.

[24]	Peiris P S, Dlamini A M. Involvement of a plasmid in exopolysaccharide production by Klebsiella oxytoc. Journal of Microbiology & Biotechnology, 1999, 15: 193-196.

[25]	方文, 吴蕾, 甘一如, 等. 肺炎克雷伯氏菌培养工艺的研究. 化学工业与工程, 2002, 19(1): 6-12.

	Fang W, Wu L, Gan Y R, et al. Chemical Industry and Engineering, 2002, 19(1): 6-12.

[26]	王桂兰, 凌沛学. 细菌胞外多糖提取分离技术研究进展. 食品与药品, 2010, 12(5): 217-219.

	Wang G L, Ling P X. Food and Drug, 2010, 12(5): 217-219.

[27]	邵德益. 微生物胞外多糖的提取. 化工时刊, 1995,8: 25-26.

	Shao D Y. Chemical Times, 1995, 8: 25-26.

[28]	宋绍富, 罗一菁, 雷光伦, 等. 微生物多糖研究进展. 油田化学, 2004, 2(1): 25-30.

	Song S F, Luo Y Q, Lei G L, et al. Oilfield Chemistry, 2004, 2(1): 25-30.

[1]	GAO Yin-ling,ZHANG Feng-jiao,ZHAO Gui-zhong,ZHANG Hong-sen,WANG Feng-qin,SONG An-dong. Research Progress of Itaconic Acid Fermentation[J]. China Biotechnology, 2021, 41(5): 105-113.

[2]	YANG Na,WU Qun,XU Yan. Fermentation Optimization for the Production of Surfactin by Bacillus amyloliquefaciens[J]. China Biotechnology, 2020, 40(7): 51-58.

[3]	WANG Meng,ZHANG Quan,GAO Hui-peng,GUAN Hao,CAO Chang-hai. Research Progress on the Biological Fermentation of Xylitol[J]. China Biotechnology, 2020, 40(3): 144-153.

[4]	WANG Bao-shi,TAN Feng-ling,LI Lin-bo,LI Zhi-gang,MENG Li,QIU Li-you,ZHANG Ming-xia. Biological Treatment Strategy Improves the Bio-accessibility of Bran Phenols[J]. China Biotechnology, 2020, 40(12): 88-94.

[5]	Qiang-qiang PENG,Qi LIU,Ming-qiang XU,Yuan-xing ZHANG,Meng-hao CAI. Heterologous Expression of Insulin Precursor in A Newly Engineered Pichia pastoris[J]. China Biotechnology, 2019, 39(7): 48-55.

[6]	Xin-miao WANG,Kang ZHANG,Sheng CHEN,Jing WU. Recombinant Expression and Fermentation Optimization of Dictyoglomus thermophilum Cellobiose 2-Epimerase in Bacillus subtilis[J]. China Biotechnology, 2019, 39(7): 24-31.

[7]	CHEN Zi-han,ZHOU Hai-sheng,YIN Xin-jian,WU Jian-ping,YANG Li-rong. *Optimizing the Culture Conditions for Amphibacillus xylanus* Glutamate Dehydrogenase Gene Engineering Bacteria**[J]. China Biotechnology, 2019, 39(10): 58-66.

[8]	REN Li-qiong,WU Jing,CHEN Sheng. Co-Expression of N-Acetyltransferase Enhances the Expression of Aspergillus nidulans α-Glucosidase in Pichia pastoris[J]. China Biotechnology, 2019, 39(10): 75-81.

[9]	Yan HUANG,Yi-rong SUN,Jing WU,Ling-qia SU. *Optimization of High Density Fermentation of Recombinant Humicola insolens* Cutinase**[J]. China Biotechnology, 2019, 39(1): 63-70.

[10]	Jun-jie ZHAO,Long ZHANG,Liang WANG,Xu-sheng CHEN,Zhong-gui MAO. Breeding and Physiological Characteristics of ε-Polylysine High-Producing Strain with Double Antibiotic Resistance[J]. China Biotechnology, 2018, 38(8): 59-68.

[11]	Fan SUN,Ling-qia SU,Kang ZHANG,Jing WU. *D-psicose 3-epimerase Gene Overexpression in Bacillus subtilis* and Immobilization of Cells**[J]. China Biotechnology, 2018, 38(7): 83-88.

[12]	Ya-chao FAN,Lin ZHANG,Xiao-shu LI,Peng-xiang WANG,Xin-wu YAO,Kai QIAO. *Study on the Fermentation of 2,3-Butanediol by Klebsiella pneumoniae* CICC10011**[J]. China Biotechnology, 2018, 38(2): 68-74.

[13]	Li-na CHENG,Hai-yan LU,Shu-ling QU,Yi-qun ZHANG,Juan-juan DING,Shao-lan ZOU. Production of Cyclic Adenosine Monophosphate (cAMP) by Microbial Fermentation——A Review[J]. China Biotechnology, 2018, 38(2): 102-108.

[14]	ZHANG Ling,WANG Nan,JIN Lv-hua,LIN Rong,YANG Hai-lin. *To Promote the Expression of Leucine Dehydrogenase in Bacillus subtilis* via Dual-Promoter and Fermentation Research**[J]. China Biotechnology, 2018, 38(12): 21-31.

[15]	LIU Cui-cui, HU Meng-die, WANG Zhi, DAI Jun, YAO Juan, LI Pei, LI Zhi-jun, CHEN Xiong, LI Xin. Metabolic Characteristics of Intracellular Trehalose Accumulation in Zygosaccharomyces rouxii[J]. China Biotechnology, 2017, 37(9): 41-47.

Viewed

Full text

Abstract

Cited

Shared

Discussed