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| Biological Activities Analysis of the Nematocyst Venom from Jellyfish Stomolophus meleagris |
| LI Rong-feng1,2, YU Hua-hua1, XING Rong-e1, LIU Song1, LI Peng-cheng1 |
1. Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China;
2. Graduate University of the Chinese Academy of Sciences, Beijing 100039, China |
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Abstract The nematocyst venom was extracted from the tentacle of jellyfish Stomolophus meleagris. Hemolytic activity, lethal activity, SOD activity and antineoplasmic activity of the nematocyst venom was studied and the results showed that approximately 10.5μg/ml of the venom resulted in 50% hemolysis of the erythrocyte suspension and the half lethal dose (LD50) of the venom was about 50 μg venom/g fish. The total SOD activity was about 161 U/mg when the venom protein concentration was 18μg/ml and the inhibition ratio to the hepatoma Bel-7402 was up to 54.9% when the venom protein concentration was 1mg/ml. Therefore, it is of significance to study the bioactive components from the venom, which is useful for the application of the venom of jellyfish Stomolophus meleagris.
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Received: 01 December 2011
Published: 25 June 2012
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