Please wait a minute...

中国生物工程杂志

China Biotechnology
China Biotechnology  2011, Vol. 31 Issue (06): 142-148    DOI:
    
Challenges and Prospects of Tissue Engineering
DU Juan, WANG Dian-liang, ZHANG Yan-mei, SUN Jin-wei
The Second Artillery General Hospital, Beijing 100088,China
Download: HTML   PDF(510KB) HTML
Export: BibTeX | EndNote (RIS)      

Abstract  

Modern tissue engineering that can only repair simple tissue defects is still in the primary stage of development, in which many basic problems remain currently unknown. With these scientific problems gradually resolved, the definition of the term tissue engineering is also expanding, which can speed up the industrialization process of tissue engineering and promote the application of tissue engineering in clinic. The main problems and research progresses and future prospects involved in modern tissue engineering are reviewed.



Key wordsTissue engineering      Tissue engineering bioreactor      Seed cell      Scaffold material      Tissue engineered organ     
Received: 11 November 2010      Published: 28 June 2011
ZTFLH:  Q819  
Cite this article:

DU Juan, WANG Dian-liang, ZHANG Yan-mei, SUN Jin-wei. Challenges and Prospects of Tissue Engineering. China Biotechnology, 2011, 31(06): 142-148.

URL:

https://manu60.magtech.com.cn/biotech/     OR     https://manu60.magtech.com.cn/biotech/Y2011/V31/I06/142

[1] Bongso A, Fong C Y, Gauthaman K. Taking stem cells to the clinic: major challenges. J Cell Biochem, 2008,105:1352-1360.
[2] Nichols J E, Niles J A, Cortiella J. Design and development of tissue engineered lung: Progress and challenges.Organogenesis, 2009,5(2):57-61.
[3] Sharma R, Greenhough S, Medine C, et al. Three-dimensional culture of human embryonic stem cell derived hepatic endoderm and its role in bioartificial liver construction. J Biomed Biotechnol,2010,2:36-47.
[4] Sailon A M, Allori A C, Davidson E H, et al. A novel flow-perfusion bioreactor supports 3D dynamic cell culture.J Biomed Biotechnol,2009,873-816.
[5] Turner S, Wong H P, Rai J, et al.Telomere lengths in human oocytes, cleavage stage embryos and blastocysts. Mol Hum Reprod.2010,16(9):685-694.
[6] Danielsson C, Ruault S, Simonet M, et al. Polyesterurethane foam scaffold for smooth muscle cell tissue engineering. Biomaterials, 2006,(27):1410-1415.
[7] Gong Y, Zhou Q,Gao C, et al. In vitro and in vivo degradability and cytocompatibility of poly(L-lactic acid) scaffold fabricated by a gelatin particle leaching method. Acta Biomaterialia,2007,(3):531-540.
[8] Rossello R A, Cell communication and tissue engineering. J Commun Integr Biol,2010,3(1):53-56.
[9] Mieszawska A J, Kaplan D L. Smart biomaterials-regulating cell behavior through signaling molecules. BMC Biol, 2010,8:59-65.
[10] Hench L L, Polak J M. Third-generation biomedical materials. Science,2002, 295:1014-1017.
[11] van Lenthe G H, Hagenmüller H, Bohner M, et al. Nondestructive micro-computed tomography for biological imaging and quantification of scaffold-bone interaction in vivo. Biomaterials, 2007,(28):2479-2490.
[12] Xu Q, Lu H, Zhang J, et al. Tissue engineering scaffold material of porous nanohydroxyapatite/polyamide. J Nanomedicine, 2010,5:331-335.
[13] Beachley V, Wen X. Polymer nanofibrous structures: Fabrication, biofunctionalization, and cell interactions.Prog Polym Sci, 2010,35(7):868-892.
[14] Wei G, Ma P X. Nanostructured biomaterials for regeneration. Adv Funct Mater, 2008,18(22):3566-3582.
[15] Freytes D O, Wan L Q, Vunjak-Novakovic G. Geometry and force control of cell function. J Cell Biochem,2009,108(5):1047-1058.
[16] Freed L E, Guilak F, Guo X E, et al. Advanced tools for tissue engineering: scaffolds, bioreactors, and signaling.Tissue Eng,2006,12(12):3285-3305.
[17] Niklason L E, Abbott W, Gao J, et al. Morphologic and mechanical characteristics of engineered bovine arteries. The Journal of the American Medical Association 2001,285(5):573-576.
[18] Wang D L, Liu W S, Han B Q, et al. The bioeactor: A powerful tool for large-scale culture of animal cells. Curr Pharm Biotechnol,2005,6(5):35-41.

[1] ZHU Shuai,JIN Ming-jie,YANG Shu-lin. A Review on Applications of 3D Bioprinting in Cartilage Tissue Regeneration Engineering[J]. China Biotechnology, 2021, 41(5): 65-71.
[2] YU Xing-ge,LIN Kai-li. The Application of Biomaterials Based on Natural Hydrogels in Bone Tissue Engineering[J]. China Biotechnology, 2020, 40(5): 69-77.
[3] WANG Yuan-dou,SU Feng,LI Su-ming. Research Progress of Photocrosslinked Hydrogel in Tissue Engineering[J]. China Biotechnology, 2020, 40(4): 91-96.
[4] YAN Ge,QIAO Wei-hua,CAO Hong,SHI Jia-wei,DONG Nian-guo. Application of Surface Modification of Polydopamine in Tissue Engineering[J]. China Biotechnology, 2020, 40(12): 75-81.
[5] Hui-rong WU,Zhao-hui WEN. Application of Chitosan in Nerve Tissue Engineering[J]. China Biotechnology, 2019, 39(6): 73-77.
[6] Xi KANG,Ai-peng DENG,Shu-lin YANG. Research Progress of Chitosan Based Thermosensitive Hydrogels[J]. China Biotechnology, 2018, 38(5): 79-84.
[7] XI Lai-shun,YUN Peng,WANG Yuan-dou,ZHANG Guan-hong,XING Quan-sheng,CHEN Yang-sheng,SU Feng. Application of Shape Memory Polymer in Tissue Engineering[J]. China Biotechnology, 2018, 38(12): 76-81.
[8] SUN Huai-yuan,SONG Xiao-kang,LIAO Yue-hua,LI Xiao-ou. The Application of Piezoelectric Micro-jetting Technology in the Field of Cell Bioprinting[J]. China Biotechnology, 2018, 38(12): 82-90.
[9] LI Da-wei, HE Jin, HE Feng-li, LIU Ya-li, DENG Xu-dong, YE Ya-jing, YIN Da-chuan. Advances in Application of Silk Fibroin/Chitosan Composite in Tissue Engineering[J]. China Biotechnology, 2017, 37(10): 111-117.
[10] LUO Si-shi, TANG Shun-qing. Research Progress of Agarose in Tissue Engineering[J]. China Biotechnology, 2015, 35(6): 68-74.
[11] WANG Dian-liang. Three-dimensional Construction of Tissue Organ and Concept of in situ Tissue Engineering[J]. China Biotechnology, 2014, 34(8): 112-116.
[12] WANG Dian-liang. Seed Cells[J]. China Biotechnology, 2014, 34(7): 108-113.
[13] WANG Dian-liang. The Birth and Development of Tissue Engineering[J]. China Biotechnology, 2014, 34(5): 122-129.
[14] ZHANG Zhi-qiang, HUANG Xiang-hua, ZHAO Lin-yuan. The Effects of Microenvironment on Cells and The Application of Bionics in Tissue Engineering Scaffolds[J]. China Biotechnology, 2014, 34(4): 101-109.
[15] WANG Dian-liang. Types and Applications of Tissue Engineering Products[J]. China Biotechnology, 2014, 34(11): 125-129.