Genetic Features and Modification of Clostridium acetobutylicum and Clostridium beijerinckii for Acetone Butanol and Ethanol Fermentation

2009, Vol. 29

Issue (10): 109-114 DOI:

Genetic Features and Modification of Clostridium acetobutylicum and Clostridium beijerinckii for Acetone Butanol and Ethanol Fermentation

YANG Ming¹,LIU Li-qiang¹,NIU Kun¹,JIA Juan-juan¹,LI Yin²,ZHANG Yan-ping²,WANG Zheng-pin¹

1.North China Pharmaceutical Biofuel Research Institute, Shijiazhuang 050015, China
2.Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China

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Abstract

Clostridium acetobutylicum and C.beijerinckii are extensively studied strains for producing ABE (Acetone, Butanol and Ethanol). Both acetone and butanol from ABE fermentation are widely used as important chemicals and raw materials. Butanol has been also recognized as a kind of potential biofuel or fuel additive with better performances than ethanol in the car engine tests. Genetic engineering has been broadly applied in the modification of these strains based on current industrial requirements and development of new biological technologies.The genetic features of C. acetobutylicum and C. beijerinckii, and progressive achievements on genetic manipulations of these strains were reviewed.

Key words： Butanol Clostridium acetobutylicum Clostridium beijerinckii Genetic engineering Molecular genetics

Received: 25 May 2009 Published: 29 October 2009

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. Genetic Features and Modification of Clostridium acetobutylicum and Clostridium beijerinckii for Acetone Butanol and Ethanol Fermentation. China Biotechnology, 2009, 29(10): 109-114.

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https://manu60.magtech.com.cn/biotech/ OR https://manu60.magtech.com.cn/biotech/Y2009/V29/I10/109

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